33 articles - From Friday Sep 25 2026 to Friday Oct 02 2026
Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…
meta-analyses and systematic reviews
| Am J Clin Nutr |
|---|
| Dietary Interventions for Menopausal Symptoms: A Systematic Review.
Soy-based dietary interventions may modestly improve vasomotor and psychological symptoms; however, certainty of evidence is very low. Dietary modification represents a feasible, low-risk approach, but larger, high-quality trials with standardized protocols and longer follow-up are required. Registry and registry number for systematic reviews or meta-analyses PROSPERO The Impact of Dietary Interventions on Menopausal Symptoms A Systematic Review (CRD42024610754). |
| Effect of vitamin D supplementation on bone health in Black, Asian and other non-White Ethnic adults: a systematic review and meta-analysis.
Evidence supporting vitamin D supplementation for improving bone health in non-White adults remains limited. |
RCT, clinical trials, retrospective studies, etc…
| Am J Clin Nutr |
|---|
| Adherence Patterns in a Randomized Controlled Trial of a Client-Choice Pantry-Based Food is Medicine Program.
The randomized controlled trial from which the cost estimates are reported is registered at ClinicalTrials. gov, ID number NCT06242808: Registration date: 02/05/2024. |
| Development and Validation of a Sociocultural Influences on Diet Questionnaire (SCID-Q).
SCID-Q is the first instrument to enable systematic and scalable assessment of discrete sociocultural factors associated with diet and weight management, and can be used to understand how different sociocultural factors influence diet, eating behaviors, and obesity. Additional research can support ongoing development of SCID-Q. |
| Pasture-Raised Red Meat Compared with Plant-Based Meat Alternatives Within Healthy Dietary Patterns: Effects on Polyunsaturated Fatty Acid Status and Cardiometabolic Health in a Randomized Dietary Intervention.
Among 259 lipid species, PE-O 39:6 was the only species remaining significant after correction for multiple testing (interaction p = 7.9 × 10-5; FDR = 0.020), remaining stable in the flexitarian group but declining in the vegetarian group CONCLUSIONS: Inclusion of moderate amounts of pasture-raised red meat did not adversely affect cardiometabolic biomarkers and was associated with maintenance of plasma DPA concentrations compared to a vegetarian dietary pattern incorporating PBMAs. NCT04869163 |
| Vitamin B12 status of people living in Canada: Results from the Canadian Health Measures Survey 2012-2019.
Most people living in Canada have adequate B12 status. Strong dietary associations reinforce the importance of supporting adequate intake through dietary guidance and policies on fortified foods and supplements. |
| Inflamm Bowel Dis |
| Biologics, small molecules, and extraintestinal malignancies in inflammatory bowel disease: practical questions and evidence-based answers.
Cancer treatment should not be compromised because of IBD, as chemotherapy and radiotherapy are feasible, whereas immune checkpoint inhibitors may trigger IBD flares. However, evidence remains constrained by confounding, heterogeneous populations, and limited long-term follow-up, underscoring the need for prospective safety studies. |
| Comparative effectiveness and safety of upadacitinib versus vedolizumab in anti-TNF-exposed patients with ulcerative colitis.
Upadacitinib demonstrates superior effectiveness over vedolizumab in anti-TNF-exposed UC but carries a higher burden of adverse events, highlighting the need for personalized benefit-risk assessment to guide treatment selection. |
| Comparative effectiveness of infliximab vs vedolizumab as first-line biologic therapy in moderate-to-severe ulcerative colitis: A prospective, multicenter, real-world study.
Among patients with moderate-to-severe ulcerative colitis who have not been treated with biologics before, vedolizumab-first therapy showed superior short- and long-term effectiveness vs infliximab-first therapy, with comparable safety profiles. Vedolizumab could serve as the initial biologic agent for moderate‑to‑severe ulcerative colitis.NCT06962020; Selection and Efficacy-Inducing Factors of First-Line Biologic Agents in Moderate-to-Severe Ulcerative Colitis; |
| Effectiveness, safety, and clinical outcomes of treatment with the oral α4-integrin antagonist carotegrast methyl in patients with active ulcerative colitis: a multicenter observational study (CANAL study).
In terms of patient-reported symptom improvement, carotegrast methyl is an effective and well-tolerated treatment for patients with ulcerative colitis who have an inadequate response to 5-ASA. A substantial proportion of patients responded to 8 weeks of treatment. Continued treatment for up to 16 weeks may improve symptoms, even in patients with insufficient response at week 8. |
| Fecal calprotectin changes after polyethylene glycol bowel preparation in patients with ulcerative colitis in remission.
This prospective paired-sample study evaluated fecal calprotectin changes after polyethylene glycol-based bowel preparation in ulcerative colitis patients in remission. Calprotectin increased modestly, particularly in patients with Mayo 1 endoscopic subscore, but clinical worsening was uncommon and healthy individuals showed no significant change. |
| Handheld intestinal ultrasound and the point-of-care question in pediatric IBD: a commentary.
We contend that handheld intestinal ultrasound reframes the point-of-care debate regarding timing and cost, not diagnostic superiority. For many pediatric inflammatory bowel disease programs, bridging with radiology while building training and governance remains the wisest near-term approach. |
| Incidence, risk factors, and treatment patterns of pouchitis in pediatric ulcerative colitis.
Acute and chronic pouchitis are common complications following pediatric RPC-IPAA. While pouch failure is rare, a significant percentage will require postoperative advanced IBD therapy. Families should be counseled that proctocolectomy can achieve disease control but does not eliminate the need for IBD-directed medical therapy. |
| Long-term outcomes of patients with negative small bowel video capsule endoscopy for Crohn's disease: A cohort study.
A negative VCE confers a very low likelihood of subsequent CD diagnosis in patients with suspected CD after nondiagnostic standard evaluation. Diagnostic efforts should instead focus on functional evaluation and dietary intervention. |
| J Crohns Colitis |
| Distinct intestinal eosinophil subsets in ulcerative colitis and their modulation by advanced inflammatory bowel disease therapies.
We confirmed enrichment of total eosinophils in inflamed colonic tissue, characterized by an increase in B-Eos and a reduction in A-Eos, resulting in a decreased A-Eos/B-Eos ratio. Exploratory analyses suggest that vedolizumab is associated with reduced B-Eos, increased A-Eos, and restoration of the A-Eos/B-Eos ratio, raising the hypothesis that this therapy may differentially modulate mucosal eosinophil biology. These findings identify distinct eosinophil subsets as potential biomarkers and therapeutic targets in UC and provide a biological framework for future mechanistic studies. |
| Real-world effectiveness and safety of risankizumab induction and maintenance therapy in pediatric patients with Crohn's disease: a multicenter retrospective analysis.
In this multicenter pediatric cohort, risankizumab induced meaningful clinical and biomarker improvement with durable remission and a favorable safety profile, supporting risankizumab as an effective option for children with CD. |
| Liver Transpl |
| A multidisciplinary clinic model for alcohol use disorder after liver transplantation: Implementation and early outcomes of the LIFT Clinic.
Early implementation challenges included high non-attendance, which improved following operational changes. These findings demonstrate the successful implementation of a patient-centered, integrated care model for managing AUD after liver transplantation while highlighting patient engagement as an important early implementation challenge and provide a practical model for multidisciplinary post-transplant AUD care at other transplant centers. |
| Definitive surgical outcomes in children with advanced hepatoblastoma (PRETEXT III-IV): A retrospective single-center canadian experience.
Mortality in this cohort was entirely disease-related, occurring after recurrence or progression of residual metastases rather than from surgical modality. Incorporating AFP trend, pulmonary response, and detailed imaging into preoperative assessment may help identify high-risk patients and support more informed surgical decision-making. |
| Pancreas |
| Early Detection of Pancreatic Adenocarcinoma Using Triple-phase contrast-enhanced Computed Tomography: A Case-control Study.
Finally, different attenuation of pancreatic parenchyma in each phase, MPD stenosis, and focal pancreatic parenchymal atrophy were significantly correlated with the risk of PDAC. While some findings may already appear on the pre-diagnostic CT in one-third of the PDAC-positive sections, an accurate and detailed review in triple-phase CT is indispensable to detect early PDAC in clinical practice. |
| Pancreatology |
| Longitudinal body composition changes distinguish pancreatic ductal adenocarcinoma from controls in a pre-diagnostic CT cohort.
In a CT-imaged cohort, PDAC is associated with measurable longitudinal body composition changes prior to diagnosis that differ from matched controls. These changes demonstrate moderate discrimination to distinguish cases from controls but appear to reflect processes occurring closer to clinical diagnosis. |
| Pathophysiology of sarcopenia in chronic pancreatitis: Insights from muscle biopsy and molecular profiling.
Sarcopenia is common in patients of chronic pancreatitis, and it is characterized by activation of catabolic signaling, impaired anabolic pathways, mitochondrial dysfunction, and defective autophagy. These findings are hypothesis-generating and, if confirmed in larger mechanistic studies, may help identify targets to mitigate muscle loss and improve outcomes. |
Plenty of the editorials are available as full text through the publisher website using the provided link
| Inflamm Bowel Dis |
|---|
| Interpreting therapy escalation after discordant Clostridioides difficile testing in IBD. |
| J Crohns Colitis |
| Evaluating sonographic response and remission in inflammatory bowel disease: aligning intestinal ultrasound assessment with STRIDE-II timelines.
IUS is a practical, non-invasive tool for monitoring therapeutic response in IBD. The optimal timing of reassessment is likely to vary according to therapy-specific time to response, IBD subtype, disease phenotype, and bowel segment. Standardization of definitions and reassessment timelines remain central to integrating IUS into treat-to-target models of IBD care. |
misc publications eg case reports, tools of the trade, images of the month, etc…
| Inflamm Bowel Dis |
|---|
| Postoperative weight trajectories after ileal pouch-anal anastomosis are associated with the development of Crohn's-like disease of the pouch. |
| Liver Transpl |
| From area-level deprivation to individual social risk: Rethinking social risk assessment across the hepatocellular carcinoma care continuum. |
| Letter to the Editor: Prophylactic tranexamic acid in liver transplantation-looking beyond the primary endpoint. |
| Liver transplantation from SARS-CoV-2-positive deceased donors: Thrombotic risk, graft implications, and the impact of perioperative management. |
| Reply: Prophylactic Tranexamic Acid in Liver Transplantation-Looking Beyond the Primary Endpoint. |
| Reply: Reconsidering the temporal dynamics of sarcopenia in MELD-based allocation bias-A Clinical Perspective. |
| The clot thickens: Portal vein thrombosis as a barometer of vascular disease in cirrhosis. |
| Pancreatology |
| Association of timing of onset and duration of systemic inflammatory response syndrome with the severity and outcomes of acute pancreatitis. |
Letters to the editors and authors’ replies
| Liver Transpl |
|---|
| Letter to the Editor: outcome definition, class enumeration, and transportability of machine learning-derived ascites phenotypes. |
| Letter to the editor: Reconsidering the temporal dynamics of sarcopenia in MELD-based allocation bias-A clinical perspective. |