25 articles - From Friday Mar 06 2026 to Friday Mar 13 2026
Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…
| J Crohns Colitis |
|---|
| Position Paper: IOlBD Evidence-based Consensus on the Use of Artificial Intelligence for Assessment of Endoscopic and Histologic Endpoints in Clinical Trials of Inflammatory Bowel Disease.
This IOIBD consensus supports the integration of AI/ML into central reading for IBD clinical trials to improve objectivity, efficiency, and consistency, while maintaining human oversight. Further research should address validation, regulatory frameworks, and multi-modal integration to enable broader adoption in both trials and clinical practice. |
meta-analyses and systematic reviews
| Am J Clin Nutr |
|---|
| Validity and Reliability of Tools to Measure Ultra-Processed Food Intake under the NOVA System: A Systematic Review.
Instruments assessing NOVA-defined UPF intake demonstrate acceptable reproducibility but variable, reference-dependent validity and system-specific classification uncertainty. Future research should prioritize higher-quality reference methods, transparent coding rules, calibration strategies, and routine evaluation of measurement error and responsiveness. Registry PROSPERO CRD420251135087. Prospective Registry of Systematic Reviews (PROSPERO) registration number CRD420251135087. |
| Inflamm Bowel Dis |
| Incidence of acne in patients with inflammatory bowel disease treated with Janus kinase inhibitors: a systematic review and meta-analysis.
Acne is a common adverse event in IBD patients treated with JAK inhibitors. The reported incidence of acne was significantly higher with upadacitinib, in the pediatric population, and numerically higher during the induction phase of treatment. |
| Prevalence of disability in inflammatory bowel disease: a systematic review and meta-analysis.
This systematic review is the first, to our knowledge, to show that moderate-to-severe disability affects nearly one-third of patients with IBD, with higher rates in Crohn disease and active disease. Importantly, disability persists in a substantial proportion of patients even during remission, supporting the need for systematic assessment across clinical settings. |
| Pancreatology |
| Characterisation of early-onset pancreatic adenocarcinoma molecular profile compared to average-onset pancreatic adenocarcinoma (CARAPAC): A systematic review and a meta-analysis.
EOPA is enriched in KRAS wild-type tumours. This profile may offer alternative therapeutic opportunities, including RNA-based fusion detection, inclusion in targeted therapy trials, and suggest alternative oncogenic pathways for a proportion of this subpopulation. Standardised definitions, consistent molecular reporting, and exploration of age-specific risk factors are critical to improve understanding and management of EOPA. |
| Risk factors for pancreatic exocrine insufficiency after acute pancreatitis: A systematic review and meta-analysis.
PEI affects one in five AP patients in the long term. Alcoholic AP and necrosectomy are risk factors for AP-induced PEI. PEI can develop even after mild AP. |
RCT, clinical trials, retrospective studies, etc…
| Am J Clin Nutr |
|---|
| Artificially Sweetened Beverages and Weight Change: Findings from Three Prospective Cohort Studies of U.S. Adults.
Increases in ASB intake were inversely associated with weight/BMI gains over time, particularly among adults with overweight/obesity and higher SSB intake. Replacing SSBs with ASBs -or ideally water- was associated with decreases in weight/BMI changes in a dose-dependent manner. |
| Estimating proton density fat fraction using computed tomography attenuation in skeletal muscle and adipose tissue in a prospective clinical cohort.
It is feasible to convert density values from CT scans to accurate estimates of PDFF in skeletal muscle and SAT. Conversion of tissue density values from CT HU to estimated PDFF expand clinical measures of muscle quality and improve body composition assessment. |
| Independent effects of whey protein and alkali supplementation on muscle health in healthy older adults: factorial randomized controlled trial.
Objectives To determine the effects of whey protein (WP) and alkali (potassium bicarbonate, KHCO supplement for 24 weeks improved measures of muscle power, physical performance or muscle mass despite achieving higher circulating IGF-1 levels. Clinical trial registry number NCT04048616 All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. |
| Monitoring Growth and Body Composition in Children with 3D Optical Imaging: A Pilot Observational Study.
3DO is capable of monitoring body composition changes over time in children and adolescents. The accuracy, safety, and accessibility of this approach supports its feasibility for risk screening in this population. Clinical trials number Shape Up! Kids (NCT03706612, |
| Muscle Movement and Metabolism: Exercise and Skeletal Muscle as Mediators of Health. A Report from the 26th Annual Harvard Nutrition Obesity Symposium, 2025.
This manuscript synthesizes the symposium's major themes: 1) physiological and molecular mechanisms of exercise, 2), clinical implications of physical inactivity and reduced muscle function, and 3) individual variability and personalized medicine. By bridging mechanistic and clinical insights with principles of personalized medicine, the symposium provided key insights into the current landscape of treatments for metabolic diseases and evidence-based strategies for disease prevention. |
| Prevalence and determinants of stunting, overweight, and concurrent stunting and overweight among children aged 6 to 23 months in 40 low- and middle-income countries, 2015‒2024.
Although stunting dominates in LMICs, CSO reveals 2 distinct patterns. The paradox-where maternal education reduces stunting but may raise overweight-combined with the roles of wealth and timely complementary feeding in reducing CSO, necessitates integrated, context-specific "double-duty" interventions. |
| The relationship between obesity, calorie delivery and mortality in the critically ill: a post hoc analysis of The Augmented versus Routine Approach to Giving Energy Trial.
In this post hoc study of critically ill patients receiving enteral nutrition, obesity confers a relative survival advantage to 90 d. Reduced calorie delivery is associated with increased risk of death in the group with obesity and the nonobese, but calorie threshold for the group with obesity varies according to the method of body weight calculation. This study was registered at TARGET trial clinicaltrials.gov number as NCT02306746. |
| Ultra-processed foods consumption and risk of preeclampsia. A secondary analysis of the IMPACT BCN randomized clinical trial.
In a high-risk population, a higher change in dietary intake of UPF consumption from the second to third trimester of pregnancy was associated with a higher risk of preeclampsia. |
| Inflamm Bowel Dis |
| Early Intestinal Ultrasound Assessment Predicts Therapy Response: An Easy Tool for Clinical Decision-Making.
Early reduction in BWT, especially when combined with Limberg score, is a strong predictor of TH and IUS response at 12 months, supporting the use of early IUS monitoring in clinical practice. |
| Fecal calprotectin is an accurate noninvasive screening tool for pouchitis.
FC is accurate for detecting and grading pouch inflammation. Thresholds near 167 and 280 µg/g reliably discriminate normal from inflamed pouches and mild from severe endoscopic disease, respectively. |
| Pancreas |
| Effect of Skeletal Muscle Mass Loss on Outcomes of Patients With Intraductal Papillary Mucinous Neoplasm.
Skeletal muscle mass loss was an independent risk factor for all-cause mortality, and it might be associated with the risk factor for the incidence of pancreatic cancer, particularly IPMN-derived carcinoma in patients with IPMN. Patients with a low PMI and minimal comorbidities might be better to undergo long-term surveillance due to their increased risk of pancreatic cancer. |
| Knockdown of Lymphoid Enhancer-binding Factor 1 Inhibits Pancreatic Adenocarcinoma Growth and Neoangiogenesis by Curbing Notch1 and Nuclear Factor Kappa B Signaling Pathways.
Knockdown of LEF1 can inhibit the growth and neoangiogenesis of PAAD by inhibiting Notch1 and NF-κB, thus inhibiting the malignant progression of PAAD. |
| The Transcription Factor TFAP2A Induces M2 Macrophage Polarization by Upregulating EPS8L3 Expression, Thereby Accelerating the Malignant Progression of Pancreatic Ductal Adenocarcinoma.
TFAP2A positively regulated EPS8L3 to facilitate M2 polarization of macrophages and the malignant progression of PDAC cells. |
| Pancreatology |
| Seasonal patterns and dynamics of acute pancreatitis emergency department visits in Korea.
This study demonstrated a pronounced summer peak in AP visits among both pediatric and adult populations in Korea. Campylobacter and Salmonella species may be linked to this seasonal pattern, suggesting a temporal association between infections with these species and AP seasonality. Further research is needed to clarify other mechanisms underlying seasonal AP surges and inform targeted preventive strategies. |
Plenty of the editorials are available as full text through the publisher website using the provided link
| Am J Clin Nutr |
|---|
| Individualized nutritional care for the critically ill: focus on obesity. |
| The challenge of coping with the coexistence of stunting and overweight in young children. |
| J Crohns Colitis |
| Patient knowledge and awareness on inflammatory bowel disease as it evolves as a global disease: a scoping review.
Global IBD knowledge and awareness remain inadequate and uneven across regions and domains. Updated, culturally appropriate and adaptable assessment tools and multidisciplinary, technology-enabled educational strategies are needed to enhance IBD literacy. |
misc publications eg case reports, tools of the trade, images of the month, etc…
Letters to the editors and authors’ replies
| Am J Clin Nutr |
|---|
| Alcohol use with metabolic dysfunction-associated steatotic liver disease: from denial to action. |
| Associations between domestic water hardness and risk of experiencing cardiovascular events. |