48 articles - From Friday Nov 08 2024 to Friday Nov 15 2024
Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…
meta-analyses and systematic reviews
Am J Gastroenterol |
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Family History of Colorectal Cancer and the Risk of Colorectal Neoplasia: A Systematic Review and Meta-Analysis. Family history of CRC is associated with increased risk of adenoma, NAA, AA, and AN totally, and in al available subgroups. The findings further strengthen the necessity and importance of an intensified screening strategy for individuals with a positive family history of CRC, which is very useful for related health resource allocation and policymaking. |
Gastroenterology |
Adverse Events Associated with Endoscopic Retrograde Cholangiopancreatography: Systematic Review and Meta-analysis. ERCP-associated AEs remain common. Incidence of post-ERCP pancreatitis remained static despite improvements in techniques, prevention, and recognition. These results are important to patients, endoscopists, and policy makers to inform consent and to encourage implementation of available risk mitigation strategies. |
RCT, clinical trials, retrospective studies, etc…
Clin Gastroenterol Hepatol |
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Dietary antioxidant capacity, genetic susceptibility and polymorphism, and inflammatory bowel disease risk in a prospective cohort. This study suggests that a diet with high TAC may help prevent the development of IBD, particularly in individuals at high genetic risk of IBD and in mutation carriers of rs4880 in SOD2. |
ENDOSCOPIC SEDATION TYPE DURING FLIP PANOMETRY DOES NOT SIGNIFICANTLY IMPACT FLIP MOTILITY CLASSIFICATION RELATIVE TO MANOMETRY. The proportion of HRM diagnoses within each FLIP Panometry classification also did not differ between FLIP completed with CS vs MAC with fentanyl (P=0.098) or MAC without fentanyl (P=0.0261) CONCLUSIONS: Whether CS or MAC was used as sedation during FLIP did not have a clinically significant impact on the relationship between diagnosis on FLIP Panometry and HRM. This supports the validity of diagnosing esophageal motility disorders using FLIP Panometry during sedated endoscopy. |
Influence of comorbidities on health-related quality of life in alcohol-related liver disease: a population-based survey. Common comorbidities including COPD, musculoskeletal and psychiatric disease are associated with low HRQoL in ALD, independently of liver disease severity, and so are alcohol consumption and smoking. These findings highlight the importance of multidisciplinary management of patients with ALD. |
Yield and Effectiveness of Two-Sample Fecal Immunochemical Test-based Screening Program for Colorectal Cancer. Two-sample FIT could effectively identify high-risk populations, and colonoscopy compliance is associated with a lower risk of CRC incidence and mortality. This strategy might facilitate CRC screening practice in countries with large populations. |
Endoscopy |
Feasibility of modified double-layered suturing for a large mucosal defect after duodenal endoscopic submucosal dissection (Origami method). The OGM achieved high-rate complete closure even after duodenal ESD, which was robust enough to maintain the folded muscle layer for at least 3 days postoperatively. |
Hepatology |
Hemodynamic effects of carvedilol plus simvastatin in cirrhosis with severe portal hypertension and suboptimal response to β-blockers: A double-blind, placebo-controlled, randomized-trial. In patients with severe portal hypertension (all with high-risk varices) and suboptimal hemodynamic response to traditional NSBBs, combined therapy with carvedilol plus simvastatin significantly enhances the portal-pressure reduction achieved with carvedilol-monotherapy, improves endothelial dysfunction and reduces pro-inflammatory cytokines. |
Oral LPCN 1148 improves sarcopenia and hepatic encephalopathy in male patients with cirrhosis: A randomized, placebo-controlled phase 2 trial. LPCN 1148 treatment improved sarcopenia and reduced the number of overt HE episodes in men with cirrhosis and sarcopenia awaiting liver transplant. These findings support additional research on the efficacy of LPCN 1148 in treating sarcopenia and preventing HE recurrence. |
Platelet-derived mitochondria regulate lipid metabolism in nonalcoholic steatohepatitis via extracellular vesicles. We offer a novel molecular mechanism that connects platelets, pEVs, and excessive LD accumulation to the development of NASH. Our results suggest that NASH progression may be alleviated by specifically inhibiting the production and release of pEVs, or by targeting pEVs components and inhibiting their uptake. Additional experiments are required to confirm this potentiality. |
Plenty of the editorials are available as full text through the publisher website using the provided link
Gastrointest Endosc |
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misc publications eg case reports, tools of the trade, images of the month, etc…
Clin Gastroenterol Hepatol |
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Endoscopy |
Gastroenterology |
Hepatology |
Letters to the editors and authors’ replies
Gastrointest Endosc |
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Gut |
J Hepatol |