40 articles - From Friday Oct 02 2026 to Friday Oct 09 2026
Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…
| Clin Gastroenterol Hepatol |
|---|
| AGA Clinical Practice Update on Surveillance of Pancreatic Cystic Lesions and Hepatocellular Carcinoma in Older Adults: Expert Review.
BEST PRACTICE ADVICE 9: HCC surveillance should stop if estimated life expectancy is low and is less than 1 to 2 years based on medical comorbidities, impaired functional status, or liver decompensation (eg, Child-Turcotte-Pugh C cirrhosis) where liver transplant is not an option. Shared decision-making with patients can inform HCC surveillance decisions. |
meta-analyses and systematic reviews
| Aliment Pharmacol Ther |
|---|
| Systematic Review: Inclusion of Patients With Difficult-to-Treat Inflammatory Bowel Disease in Randomized Controlled Trials of Advanced Therapies.
Few RCTs of advanced medications include patients with DTT-IBD. In most trials, participants with DTT-IBD represent a minority of the study population, and subgroup-specific data are lacking. |
RCT, clinical trials, retrospective studies, etc…
| Aliment Pharmacol Ther |
|---|
| The TOP-GERD Trial: Comparative Efficacy of Tegoprazan Versus Pantoprazole in the Treatment of Erosive Oesophagitis in a Non-Asian Population.
There was a nonsignificant 9.5% difference in the primary intention-to-treat 4-week healing endpoint between tegoprazan and pantoprazole. Tegoprazan provided faster symptom improvement, while the per-protocol findings and the higher healing rate observed in the exploratory severe oesophagitis subgroup were encouraging and warrant further investigation. (ClinicalTrials.gov Identifier NCT06991348). |
| Endoscopy |
| Impact of Repeated Endobiliary Radiofrequency Ablation on Survival in Unresectable Perihilar Cholangiocarcinoma.
Endobiliary RFA was associated with improved survival in unresectable perihilar CCA, with the benefit concentrated in the first three months after biliary drainage, at the cost of more frequent non-tumor biliary obstruction. |
| Gut |
| Clinical impact of prospective circulating tumour DNA testing for minimal residual disease in colorectal cancer: the INTERCEPT programme experience.
ctDNA testing provides a framework for risk stratification and defines temporal windows that may inform future interventional strategies. Prospective interventional studies are required to define clinical utility and optimal implementation. |
| Hepatology |
| Efficacy and safety of an 8-week bemnifosbuvir and ruzasvir regimen in chronic hepatitis C: Results from a Phase 2 study.
An 8-week treatment with bemnifosbuvir and ruzasvir resulted in high rates of SVR12 across genotypes, regardless of the presence or absence of baseline RASs, and was well tolerated among treatment-naïve HCV patients. |
| Reciprocal cross-species infection potential of human and domestic cat hepatitis B viruses.
These findings suggest a marginal zoonotic risk of DCHBV for humans and support domestic cats as a potential immunocompetent animal model for HBV research. |
| TESERA: morphologic subtyping and prognostic stratification of hepatocellular carcinoma from H&E whole-slide images.
Released as a publicly accessible pipeline applicable to H&E WSIs, TESERA unifies morphologically derived metabolism-versus-proliferation subtypes with an externally validated, prognostic morphologic index competitive with existing clinical and molecular markers. These findings position routine histology as a low-cost, widely available substrate for biology-aware risk stratification in HCC. |
| J Hepatol |
| Survival outcomes after liver transplantation in acute-on-chronic liver failure: A prospective study.
Patients with severe ACLF who underwent LT showed markedly better survival outcomes than those who were declined. Patients with five or six organ failures had high risk of post-LT death cautioning against routine LT in this population. Clinical trial number ClinicalTrials.gov number, NCT04613921. |
Plenty of the editorials are available as full text through the publisher website using the provided link
| Aliment Pharmacol Ther |
|---|
| Editorial: When the Diagnosis is Uncertain, Can AI be Certain Enough? |
| Review Article: Beyond the Therapeutic Ceiling in Inflammatory Bowel Disease-Mechanism-Based Positioning and Emerging Therapeutic Strategies.
Contemporary IBD management is increasingly defined by mechanism-based therapeutic positioning rather than simply expanding treatment options. Ongoing advances in comparative effectiveness research, novel therapeutic targets, and treatment strategies have the potential to further individualise care and improve long-term patient outcomes. |
| Clin Gastroenterol Hepatol |
| Artificial Intelligence in MASLD: A Three-Level Framework Across Clinical, Health-System, and Policy Decisions.
No randomized trial has yet demonstrated that AI-guided management improves clinical outcomes in MASLD, while governance, transparency, and equity frameworks remain underdeveloped. Realizing the clinical value of AI will require prospective multicenter studies embedded within clearly defined MASLD care decisions, validation across genetically and socioeconomically diverse populations and health-system settings, standardized reporting and risk-of-bias assessment, and sustained attention to implementation, governance, and equity. |
| Modern Diagnosis and Management of Acid-Related Disorders.
Also, diagnosis and therapy are increasingly being personalized based on symptom profile and adjunct diagnostic data from an increasingly complex armamentarium of modalities. Therapeutic algorithms demonstrate the appropriate use of many of the technologies noted above in the care of patients with acid-related disorders. |
| Pay Gap Persists for Women in Academic Gastroenterology: An Analysis of the AAMC Salary Database 2020-2025. |
| TREAT-TO-TARGET IN INFLAMMATORY BOWEL DISEASE: PROMISE, PERILS, AND THE PATH FORWARD.
We propose a framework for individualising treat-to-target decisions based on disease history, inflammatory trajectory, therapeutic options, and patient preferences. Ongoing trials including QUOTIENT, VERDICT, and VECTORS may define whether the second pillar can be placed on as firm a footing as the first. |
| Gut |
| Regulatory T cells in autoimmune liver diseases.
We further evaluate current and emerging Treg-targeted therapeutic strategies, ranging from restoration of Treg abundance and function to disease-specific modulation of Treg responses, together with the major challenges to their clinical translation. By integrating these findings, we provide a disease-dependent and context-dependent framework for understanding Treg dysregulation in AILDs and identify key priorities for future mechanistic and translational research. |
| J Hepatol |
| SETDB1: an epigenetic gatekeeper of antitumor immune organization in HCC. |
misc publications eg case reports, tools of the trade, images of the month, etc…
| Am J Gastroenterol |
|---|
| 2026 CME Information. |
| Calendar of Courses, Symposiums and Conferences. |
| Endoscopy |
| A novel device-assisted endoscopic ultrasonography-guided single balloon-occluded gastrojejunostomy bypass with a three-dimensional-printed three-way connector. |
| A rare case of curative endoscopic submucosal dissection of a duodenal gastrinoma revealed by Zollinger-Ellison syndrome. |
| Endoscopic removal of a date pit masquerading as an appendicolith in a young patient with recurrent right lower quadrant pain. |
| Endoscopic submucosal dissection versus transanal surgery for rectal neoplasia: are we asking the right question? |
| Gel-immersion peroral cholangioscopy facilitates targeted sampling of a liver abscess. |
| Modified peroral endoscopic myotomy for a bilobed Zenker's diverticulum: one incision, three tunnels, and two myotomies. |
| Utility of narrow-band imaging plus texture and color enhancement imaging mode in the evaluation of a rectal superficially serrated adenoma overlying a surgical scar. |
| Gastroenterology |
| A Cracked-Mud Duodenum in a Man With Weight Loss and Arthralgia. |
| A Rare Cause of Recurrent Vomiting: Diagnosis and Management. |
| Insights into Sensing Mechanical Forces to Guide Liver Regeneration. |
| a 19-year-man with ileocecal lesion, perinephric inflammation and recurrent obstruction. |
| Gut |
| When colonic ulcers meet destructive nasal lesions and cutaneous ulceration: a diagnostic dilemma. |
| Hepatology |
| Hepatogenesis through interspecies chimerism - An immunological path distinct from xenotransplantation. |
Letters to the editors and authors’ replies
| Aliment Pharmacol Ther |
|---|
| Letter: Does Adherence-Selected Follow-Up Establish the Benefit-Harm Balance of Population Coeliac Disease Screening? Authors' Reply. |
| Letter: P-CAB Versus PPI for Antithrombotic Gastroprotection: The Importance of Longitudinal Treatment Dynamics-Authors' Reply. |
| Letter: Proton Pump Inhibitor Prescribing in Autoimmune Gastritis-From Real-World Exposure to Indication-Driven Reassessment. Authors' Reply. |
| Letter: The Q425R Variant in Chronic Hepatitis Delta-Distinguishing Cirrhosis Prevalence From Portal Hypertension Severity. |
| Clin Gastroenterol Hepatol |
| Anchored Exposures, Competing Risks, and Impossible Statistics: Mental Health-Hepatocellular Carcinoma in Veterans. |
| Rebuttal to "Anchored exposures, competing risks and impossible statistics: mental health-HCC in Veterans". |
| Gut |
| Diabetes status stratifies the association between gut microbiome and sarcopenia. |
| Symptom-based classification of paediatric disorders of gut-brain interaction in early childhood: safeguarding against missed intestinal pseudo-obstruction. |