132 articles - From Friday Jul 10 2026 to Friday Jul 17 2026
Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…
| Am J Gastroenterol |
|---|
| Dietary Guidelines 2025-2030 For Americans Are Concerning For Liver Health.
HEI-2020 and z-score models identify multiple protective and adverse dietary components associated with SLD and fibrosis. The findings underscore the importance of component-level nuance-particularly regarding protein sources and alcohol intake-when formulating dietary guidance for liver health. |
| Endoscopy |
| Curriculum on management of acute upper gastrointestinal bleeding: European Society of Gastrointestinal Endoscopy (ESGE) Position Statement.
Abstract 19: Endoscopists should continue a period of tracking results and mentored practice with an experienced colleague for at least 6 months after achieving competence in managing UGIB. Abstract 20: As trainees move to independent practice, they should have established access to or referral pathways for key supporting specialties involved in the nonendoscopic management of acute UGIB (including emergency medicine, surgery, and interventional radiology). |
| Gut |
| International consensus on intestinal epithelial barrier assessment and therapeutic effects in inflammatory bowel diseases clinical trials.
Additional statements focused on the selection and standardisation of tools for intestinal barrier assessment, encompassing imaging-based techniques, functional permeability assays and endogenous biomarkers, as well as considerations for implementation and future research directions. This international consensus provides a structured framework to guide the design of future clinical trials evaluating efficacies of therapies in restoring intestinal barrier integrity and/or function in IBD. |
| Risk-based pathology reporting after endoscopic submucosal dissection for early gastrointestinal cancer: international consensus standards.
These consensus standards provide immediately implementable, synoptic-ready pathology reporting criteria after ESD. By standardising measurement landmarks, margin terminology, ancillary stain use and reporting of adverse histological features, they aim to reduce interinstitutional variability, improve multidisciplinary decision-making and support future validation of risk models in early gastrointestinal cancer. |
| The 2026 British Society of Gastroenterology guidelines on the diagnosis and management of adult coeliac disease.
This update is prompted by recent advancements in the diagnosis and treatment of adult CD. The primary goal is to emphasise evidence-based practices to enhance the management of adult CD, with the aim of improving patient care. |
| J Hepatol |
| Delphi Consensus in Primary Biliary Cholangitis: Collective Introspection to Set a Forward Path. |
meta-analyses and systematic reviews
| Aliment Pharmacol Ther |
|---|
| Meta-Analysis: Chronic Gastrointestinal Symptoms and Comorbidities in Hypermobile Ehlers-Danlos Syndrome and Hypermobility Spectrum Disorders.
Overall, > 60% of hEDS/HSD patients report chronic GI symptoms. DGBI, co-morbidities, including POTS, were highly prevalent in hEDS/HSD patients. However, the quality of the evidence is low due to significant clinical heterogeneity observed in the analyses. While the associations may suggest a causal relationship, the results should be interpreted with caution. |
| Meta-Analysis: Crohn's Disease Exclusion Diet for Induction and Maintenance in Crohn's Disease.
CDED-based dietary interventions appear to be efficacious for inducing remission in Crohn's disease. Well-designed randomised trials are required to further validate the use of CDED as a whole food approach in the induction and maintenance of remission in Crohn's Disease. |
| Meta-Analysis: Redefining Liver Disease Risk in Heterozygous Alpha-1 Antitrypsin Deficiency.
Heterozygous SERPINA1 genotypes are bona fide liver risk states, with effect sizes comparable to established genetic and environmental determinants. MZ/SZ heterozygosity should be recognized as moderate-penetrance liver susceptibility genotypes in chronic liver disease risk assessment. |
| Clin Gastroenterol Hepatol |
| Epidemiology of Alcohol-Associated Hepatitis: A Systematic Review of Population-Based Studies.
The global burden of AH remains poorly characterized. Existing population-based estimates are highly heterogeneous, reflecting differences in case definitions as well as probable true epidemiological variation across countries, and collectively suggest an increasing trend over the past 25 years. These findings underscore the urgent need for prospective studies employing standardized and harmonized methodologies to more accurately define the burden of this condition. |
| Timing of Antiplatelet and Anticoagulant Therapy Resumption Following Gastrointestinal Bleeding: A Systematic Review and Meta-Analysis.
Both APT and ACT resumption after GIB provide substantial clinical benefits despite increased recurrent GIB risk. Early resumption (≤7 days) offers favorable benefit-risk balance. |
| Endosc Int Open |
| Comparative Efficacy and Safety of Bariatric Surgery and Bariatric Endoscopy for Obesity Management: A Network Meta-Analysis.
Bariatric endoscopy offers a favorable safety profile and clinically meaningful weight loss, representing a minimally invasive treatment option for obesity management and metabolic improvement. |
| Endoscopy |
| Computer-aided quality assurance versus standard colonoscopy: A systematic review and meta-analysis of randomized-controlled trials.
CAQ significantly improved ADR and the detection of clinically significant lesions.While findings for AADR and ACDR should be interpreted with caution due to low event rates, the improvements in adenomas ≥10mm and APC suggest that CAQ may lower the risk of postcolonoscopy colorectal cancer, a hypothesis that warrants evaluation in future long-term analyses of patient outcomes. |
| Detection of adenoma, serrated lesion, and colorectal cancer in Lynch syndrome: a systematic review and meta-analysis.
This study characterized neoplasia detection in Lynch syndrome and confirmed higher detection rates with high-quality procedures, supporting the need to benchmark quality standards and neoplasia detection outcomes. |
| Gut |
| Outcome scoring systems for locoregional therapy in hepatocellular carcinoma: a systematic review.
Several outcome scoring systems are promising for specific LRTs and populations. However, most models have high risk of bias, underscoring the need for further development and validation. |
RCT, clinical trials, retrospective studies, etc…
| Aliment Pharmacol Ther |
|---|
| Antiviral Therapy and Post-Resection Outcomes in Patients With Hepatitis B Virus-Related Hepatocellular Carcinoma.
The choice of antiviral regimen was not associated with RFS after curative resection for HBV-related HCC, whereas TDF was independently associated with improved OS compared with ETV. Further large-scale studies are warranted to validate the long-term prognostic impact of TAF. |
| Impact of Inflammatory Activity on Anorectal Function in Patients With Ulcerative Colitis: A Prospective Study.
Inflammatory activity in UC impairs anorectal function by increasing rectal sensitivity and reducing rectal compliance and capacity, contributing to persistent symptoms. Ongoing dysfunction after remission highlights the need for diagnostic and therapeutic strategies addressing anorectal involvement. |
| Inflammatory Bowel Disease Is Associated With an Increased Risk of End-Stage Renal Disease: A Population-Based Cohort Study.
Persons with IBD have an increased risk of ESRD by nearly 50%, with CD showing a greater risk than UC. Bowel surgery, allopurinol use and oral steroid therapy are important predictors, emphasising the necessity of careful renal monitoring in IBD patients. |
| Long-Term Safety and Efficacy of Obeticholic Acid in Patients With Primary Biliary Cholangitis: Final Results of the POISE Long-Term Safety Extension.
Findings from the POISE OLE support the safety and efficacy profile of long-term OCA treatment for patients with PBC with inadequate response or intolerance to UDCA (NCT01473524). |
| Real-World Effectiveness, Safety and Quality of Life With Ustekinumab for the Treatment of Crohn's Disease: Results of the UK Ustekinumab Real World Evidence Study (UndieS) Study Group.
In this large real-world cohort, ustekinumab treatment was associated with sustained improvements in both clinical outcomes and QoL measures. Our data suggest that patients treated in clinical practice differ markedly from Phase 3 trial participants. QoL, and not only disease activity as assessed using a conventional disease activity score, may play a significant role in the decision to initiate ustekinumab. Systematic integration of QoL measures into routine care may improve patient care and treatment outcomes. |
| Am J Gastroenterol |
| Association of Intrapancreatic Fat Deposition with Mortality: A Prospective Cohort Study with Genetic Risk Profiling.
Excessive IPFD is associated with elevated risk of future mortality especially from vascular diseases in the general population. |
| Dose May Matter: CYP2C19 Genotype and PPI Response in Pediatric Eosinophilic Esophagitis.
Knowing CYP2C19 genotype may optimize PPI dose for the treatment of EoE in individual patients. |
| Dupilumab Improves Endoscopic Features in Children Aged 1-11 Years With Eosinophilic Esophagitis: EoE KIDS Study Results.
Dupilumab improved endoscopic features of EoE at Week 16 vs placebo, and improvements were sustained up to 52 weeks. A greater proportion of patients treated with continuous dupilumab achieved endoscopic normalization at Week 52 compared with those who switched to dupilumab at Week 16. |
| Clin Gastroenterol Hepatol |
| Artificial Intelligence-Enabled Opportunities to Reduce Administrative Bloat in Gastroenterology Practices: Scoping Review.
Commercialized products were broadly designed, least validated, and scored lowest on FAIR-AI metrics, particularly Fairness, while GI-specific products with greater methodological rigor remained largely pre-commercialized. Commercial general-platform products lacked GI-specific validation, and high-burden specialty workflows including hepatology care coordination and transplant documentation remained comparatively underserved. Realizing the potential of administrative AI in gastroenterology requires moving toward empirically validated, specialty-specific, and equitable solutions, where success is measured by reduced administrative burden and time returned to patient care, not by revenue generation. |
| Per- and polyfluoroalkyl substances (PFAS) in early life is associated with childhood intestinal inflammation: analyses of three birth cohorts.
PFAS chemicals are detectable in early life samples, indicating exposure during this period of vulnerability, and are associated with higher FC in childhood across three birth cohorts. |
| Time trends in strategies for postoperative Crohn's disease management and long-term surgical recurrence: ENEIDA registry data.
Medical prevention for POR after the first intestinal resection for CD increased significantly in the last two decades, alongside the use of biologicals to treat POR. These changes were associated with a significant decrease in the cumulative probability of surgical POR. |
| Vibration-controlled transient elastography-based prevalence of MASLD in Saudi Arabia: A prospective cohort study.
MASLD affects more than one-third of Saudi adults and is associated with central obesity and metabolic dysfunction, while significant fibrosis remains relatively low. These findings provide the first prospective, population-level MASLD estimates at a country level in Saudi Arabia and support scalable VCTE-based risk stratification. |
| Endosc Int Open |
| Automatic Evaluation of Small Bowel Cleanliness in Capsule Endoscopy: A Comparative Study of Four Preparations using Artificial Intelligence.
We demonstrated using an AI-based tool, that LD provides adequate preparation for SBCE, questioning the routine administration of laxatives and supporting a patient-centered approach. |
| Feasibility and Safety of Endoscopic Vacuum Therapy of Walled-Off Necrosis in Acute Necrotizing Pancreatitis.
Intracavitary EVT is feasible and relatively safe in treating patients with WON. Larger prospective trials are necessary to evaluate a potential adjunctive benefit of EVT in this challenging patient cohort. |
| Maximising Efficient Endoscopy Training-Implementation Analysis of a Tool to Improve Endoscopy Training.
Although the findings arose from a simulated environment, the exercise provided insights into implementation barriers that can inform and strengthen subsequent real-world deployment. Further evaluation in routine clinical settings is necessary to determine its potential to support progression towards JAG certification and Certificate of Completion of Training (CCT). |
| Randomized Trial of Hood With or Without Wing Attachment-Assisted Colonoscopy With Linked Color Imaging and Computer-Aided in Adenoma Detection.
ELC demonstrated a significant improvement in the ADR compared to the TLC approach, particularly for diminutive and sessile adenomas. This superiority was consistent across varying levels of endoscopist experience, indicating broad clinical applicability. |
| Structured Cap-assisted Margin Assessment Reduces Residual Neoplasia after Colorectal Polypectomy: A Prospective Multicentre Proof-of-Concept Study.
Structured cap-assisted margin inspection substantially reduced histology-confirmed residual neoplasia in this proof-of-concept study. These findings support evaluation of margin-focused inspection and clearance strategies in larger studies. |
| Endoscopy |
| Evaluating human-AI interaction in optical diagnosis of early colorectal carcinoma through endoscopist responses to simulated artificial intelligence: a multinational online study.
Inappropriate AI response is an issue in human-AI interaction for the optical diagnosis of CRCs. Before using AI, endoscopists could inform themselves on their own and AI's optical diagnostic performance to possibly improve interaction. |
| Gastroenterology |
| A DR5/Ligase 3-mediated feedback loop perpetuates immunogenicity in mismatch repair deficient colorectal cancer.
This feedback mechanism is critical for the response to ICI therapy in mice, which is supported by a significant association between DR5 or LIG3 expression and the efficacy of ICI therapy in cancer patients. Our results reveal a functional link between dMMR and antitumor immunity, which may be useful for improving ICI therapy in tumors with different MMR statuses. |
| Harmonized metagenomic signatures of the gut microbiome reveal robust species, functions, and strain links to inflammatory bowel disease.
Microbial clades responsible for IBD-linked dysbiosis are not uniform, and their functionality in IBD and CD/UC subsets are driven by species and strain lineage-specific variants. |
| Long-term incidence of hepatocellular carcinoma after hepatitis B surface antigen seroclearance.
Patients with CHB who clear HBsAg at younger ages, particularly men <40 years and women <50 years without cirrhosis or additional risk factors, have very low HCC risk and may not require routine surveillance. |
| SOX9-driven SPEM cell lineage plasticity is a potential therapeutic target that mitigates risk of metaplastic progression to gastric cancer.
These results demonstrate that SOX9 is a master regulator of SPEM cell lineage evolution and metaplasia progression. Therefore, SOX9-mediated SPEM cell plasticity is a central mechanism in carcinogenesis. |
| Gastrointest Endosc |
| Advanced and Salvage Techniques for Difficult Biliary Cannulation in ERCP: A Randomized Trial of Outcomes and Efficacy.
DGT, TPS, and precut fistulotomy achieved comparable efficacy and safety in patients with DBC. The selection of salvage technique should be individualized and based on patient anatomy, operator expertise, and local resources. |
| Comparison of Fully Covered Self-Expanding Metal Stents and Liquid Nitrogen Spray Cryotherapy for Malignant Esophageal Adenocarcinoma: A Retrospective Cohort Study.
In this retrospective study, both FCSEMS and cryodilation are effective palliative options for malignant esophageal obstruction. Cryodilation was associated with fewer adverse events, while clinical success rates were comparable. Both modalities have distinct roles in a multidisciplinary palliative strategy, and prospective studies are needed to guide patient selection. |
| Incidence and risk factor of stricture after endoscopic submucosal dissection in the duodenal bulb.
Stricture developed in 5% of cases after ESD in the duodenal bulb and was associated with larger defects, pyloric resections, and triamcinolone injection. |
| Gut |
| Cross-definition GWAS of IBS in 2.8 million individuals reveals cardiometabolic and triglyceride-linked mechanisms.
This study provides the most comprehensive assessment of IBS genetics to date, demonstrating reproducible polygenic inheritance. We link IBS risk to convergent neurogastrointestinal and novel cardiometabolic mechanisms, highlight specific biological pathways and actionable mechanisms and outline translational opportunities emerging from integrated computational analyses. |
| Cryptogenic steatotic liver disease: a lean phenotype associated with increased liver-related mortality.
Operationally defined cryptogenic SLD accounted for a substantial proportion of lean SLD. Despite no recorded CMRFs, this phenotype was associated with liver injury markers and liver-related mortality. |
| Multimodal C9-66 CAR-T cell immunotherapy improves outcome in preclinical models of pancreatic cancer.
C9-66 CAR-T cells with metabolic optimisation and TME reprogramming represent a tumour-specific and clinically translatable immunotherapeutic strategy for PDAC and other ofCS-expressing solid tumours. |
| Neutrophil extracellular traps induced by tumour-derived NGAL reprogram CAF subtypes via ITGA5 to promote tumour progression in pancreatic cancer.
We define an IL-17/NGAL/NETs/ITGA5 axis linking neutrophil-derived extracellular DNA to iCAF specification and immunosuppression in PDAC. Cotargeting IL-17 and ITGA5 synergises with PD-1 blockade, providing a rationale for combinatorial immunotherapy. |
| Piezo2<sup>+</sup> mechanosensory neurons and glial cells initiate resident macrophage activation in postoperative ileus.
Our findings reveal activation of Piezo2-expressing enteric neurons and EGCs as a very early step in IM-induced inflammation of POI. These cells subsequently activate mMfs resulting in upregulation of Ccl4, further amplifying the inflammatory cascade. These results highlight a key role for Piezo2 in the pathophysiology of POI. |
| Hepatology |
| Context-dependent STAT3 signaling in liver fibrosis.
Current evidence most consistently supports a pro-fibrotic role for STAT3 activation in HSC-centered fibrogenic programs, whereas several PTM-dependent, metabolic, and cell-protective mechanisms remain context-restricted or incompletely validated. Herein, we provide a structured narrative synthesis of STAT3 regulation in liver fibrosis, dissect the current status and challenges of targeted therapeutic strategies, and discuss how context-matched STAT3 modulation may inform future anti-fibrotic strategies. |
| J Hepatol |
| A machine learning approach to non-invasive prediction of hepatic decompensation in compensated advanced chronic liver disease: the CIRI model.
These findings are important for clinicians and researchers aiming to identify patients with cACLD who are at increased short-term risk of hepatic decompensation. Pending further prospective validation, CIRI could support scalable and repeatable risk stratification and help guide surveillance intensity and targeted strategies intended to prevent hepatic decompensation for high-risk patients. |
| Disruption of carbon metabolism by the hepatic mononuclear phagocytic system drives liver injury in a mouse model of severe dengue.
The administration of fostamatinib ameliorated hepatic carbon metabolic disorders and liver injury. This provides a theoretical foundation for the development of therapeutic interventions targeting hepatic injury in severe dengue. |
| IgA-Enriched Phenotype Predicts Liver-Related Events in MASLD.
A data-driven clustering strategy identified a novel MASLD subtype characterized by enhanced IgA-mediated immune activation along the gut-liver axis as a key determinant of disease progression. This IgA-based stratification improves risk assessment and enables mechanism-based therapeutic targeting in high-risk MASLD patients. Impact and implications This study identified a high-risk MASLD subgroup characterized by elevated IgA levels and increased incidence of liver-related events, independent of fibrosis severity. These findings highlight the relevance of immune dysregulation, particularly IgA-associated responses, in MASLD progression. |
| Impact of non-selective beta-blockers on acute kidney injury outcomes in patients with decompensated cirrhosis.
NSBB use at AKI diagnosis was associated with improved renal recovery and survival in patients with acutely decompensated cirrhosis and AKI. Continuation during hospitalization does not appear harmful, supporting careful individualized management rather than systematic withdrawal. Impact and implications Owing to potential adverse hemodynamic effects, current guidelines recommend discontinuation of non-selective beta-blockers (NSBB) in patients with Acute Decompensation (AD) of liver cirrhosis and Acute Kidney Injury (AKI). However, this recommendation relies largely on expert opinion, since robust clinical evidence is lacking. This study prospectively evaluated the impact of NSBB on AKI outcomes in a large multicentre cohort of patients with AD and AKI. Treatment with NSBB at AKI diagnosis was associated with greater likelihood of AKI resolution and lower risk of 28-day mortality, while no evidence of an association between early discontinuation and improved outcomes was observed. These findings support a personalized approach to NSBB management in decompensated patients with AKI and highlight the need to identify patients who may benefit most from NSBB discontinuation. |
| Setdb1 represses anti-tumor immunity and tertiary lymphoid structures in hepatocellular carcinoma.
Our study has revealed a critical role for Setdb1 in TLS formation and suggests a potential role for Setdb1 as a therapeutic target for enhancing the effects of immunotherapy in HCC. Impact and implications The current study found that Setdb1 depletion induces the formation of Tertiary lymphoid structures (TLSs) in hepatocellular carcinoma (HCC). TLSs are ectopic lymphoid structures in chronic inflammation or tumors in peripheral tissues, and mature TLSs are associated with clinical advantages of tumor immunotherapy. The study discovers a new pathway involving cGas/Cxcl12 for TLS formation, which will benefit the investigations about the mechanistic regulation of anti-tumor immunity. It also provides a promising strategy to combine SETDB1 inhibition with immunotherapy in drug design and HCC treatment. |
Plenty of the editorials are available as full text through the publisher website using the provided link
| Aliment Pharmacol Ther |
|---|
| Editorial: MASLD In Primary Care-Risk-Stratification as the First Step to Treatment. |
| Editorial: Prediction of Survival in Hepatocellular Cancer-Rise and Fall of the Machines. |
| Editorial: Risankizumab in Refractory Crohn's Disease-From Real-World Effectiveness to Strategic Positioning and Early Monitoring. |
| Clin Gastroenterol Hepatol |
| Evaluating Artificial Intelligence Studies in Gastroenterology: A CGH Editors' Viewpoint. |
| Endosc Int Open |
| And Artificial Intelligence Created the Polyps…. |
| Gastroenterology |
| Finding the Signal in the Noise: Can Fecal Microbiota Transplantation Deliver for Irritable Bowel Syndrome? |
| Molecular Subtypes of Cholangiocarcinoma and their Translational Implications.
In addition, we review; the impacts of common genetic variants and known pathogenic germline or somatic variants which predispose carriers to cholangiocarcinoma. Finally, we discuss the role of epigenetics and variations in DNA methylation in heterogeneity of cholangiocarcinoma within the context of evolving treatment options and remaining key gaps in knowledge. |
| Gastrointest Endosc |
| A note from the Editor-in-Chief. |
| Beyond white light: augmenting vision in complex endoscopic surgery. |
| Breaking free from fluoroscopy: Is radiation-free cholangioscopy an achievable dream? |
| Endoscopic reversal of Roux-en-Y gastric bypass: toward a less invasive solution. |
| Endoscopic ultrasound-guided gastroenterostomy for the palliation of patients with malignant gastric outlet obstruction: stent dysfunction at the end of life. |
| Endoscopic ultrasound-guided transjugular intrahepatic portosystemic shunt? Not exactly. |
| Lumen apposing metal stents: Use in luminal stricture management. |
| Malignant gastric outlet obstruction: Does a "best" treatment option exist? |
| Routine terminal ileal intubation: reconsidering its role in screening colonoscopy. |
| Shunting or occluding? Evolving strategies for gastric varices in the era of endoscopic ultrasound. |
| The challenges of Barrett's esophagus therapy: when to treat and when to refer. |
| Toward a "dream" stent for malignant biliary obstruction: one that allows patients-and endoscopists-to sleep soundly at night. |
| J Hepatol |
| Surveillance of patients at risk of liver cancer: Expert opinions.
Many risk prediction models exist, and they have been implemented for patients with chronic hepatitis B. Stronger evidence, persistent advocacy, and consultations with national and international screening committees could pave the way for improved liver cancer surveillance practices. |
| Unveiling the Biology of Liver Fibrosis: A Miniseries on the Mechanisms, Diagnostics, and Reversibility of Liver Fibrosis. |
misc publications eg case reports, tools of the trade, images of the month, etc…
| Am J Gastroenterol |
|---|
| BEHÇET'S SYNDROME PRESENTING AS SEVERE ULCERATIVE ESOPHAGITIS: A DIAGNOSTIC CHALLENGE. |
| Calendar of Courses, Symposiums and Conferences. |
| Correction to Efficacy of Tenapanor in Treating Patients With Irritable Bowel Syndrome With Constipation: A 26-Week, Placebo-Controlled Phase 3 Trial (T3MPO-2). |
| Correction to: Computer-Aided Colonoscopy Alert Fatigue and Its Effect on Adenoma Detection. |
| Designing and Interpreting Large Database Studies in GI and Hepatology. |
| How I manage cirrhosis in a busy outpatient clinic? The P.O.R.T.A.L.V.E.I.N. mnemonic. |
| Clin Gastroenterol Hepatol |
| Educating the Artificial Intelligence-Augmented Clinician: Theories and Frameworks for Artificial Intelligence-Enhanced Education in Gastroenterology. |
| Longitudinal assessment of clinical risk scores for HCC in patients with cirrhosis. |
| Low Sensitivity of Commercial Assays for Measles Seroprotection in Adult Patients with Inflammatory Bowel Disease. |
| Endoscopy |
| Dual-hook clip closure for high-tension gastric defects. |
| Endoscopic closure of a perforated peptic ulcer using a detachable snare loop in an elderly patient at high risk for surgery. |
| Endoscopic full-thickness retrieval of a migrated plastic stent after endoscopic ultrasonography-guided liver abscess drainage. |
| Endoscopic retrieval of an impacted pancreatic duct basket using a cystotomy knife: A case report. |
| Endoscopic salvage of a N-butyl cyanoacrylate-occluded gastroscope using cholangioscopic electrohydraulic lithotripsy. |
| Human-artificial intelligence adaptation in colonoscopy: beyond deskilling and upskilling. |
| Infected walled-off necrosis: upfront necrosectomy for some, optimized step-up for all. |
| Internal traction combined with pre-suturing assisted endoscopic submucosal dissection for the treatment of a giant polypoid lipoma of the terminal ileum. |
| Ligation-assisted mucosal unroofing and snare resection: a simplified and cost-effective technique for gastric submucosal tumors. |
| Reverse rendezvous endoscopic retrograde cholangiopancreatography after liver partition and portal vein ligation. |
| Single-balloon enteroscope-bridged endosonography-guided gallbladder drainage with lumen-apposing metal stent in Billroth II. |
| Successful electrohydraulic lithotripsy of an enterolith in Crohn's disease using a small-caliber double-balloon endoscope. |
| Successful retrieval of a misdeployed stent using a drill dilator during endoscopic ultrasound-guided hepaticogastrostomy: a useful technique with a potential pitfall. |
| Gastroenterology |
| Long term follow-up from the Barrett's esophagus screening trial 3 (BEST3) demonstrates high negative predictive value of capsule-sponge-Trefoil-factor-3 (TFF3) test for esophageal adenocarcinoma. |
| Nutrition and Body Composition: Missing Outcomes in Appetite- and Weight-Modifying Therapies for Individuals with Inflammatory Bowel Disease. |
| The many challenges of necrotizing pancreatitis. |
| Gastrointest Endosc |
| Charcoal gum-associated pseudomelanosis ilei with aluminum and titanium enrichment on elemental analysis. |
| Cold snare avulsion pseudoperforation. |
| Endoscopic findings of autoimmune gastritis with coexisting collagenous gastritis in an adolescent. |
| Intraductal biliary plasmacytoma presenting as obstructive jaundice: a case report. |
| Unmasking Kaposi sarcoma: isolated rectal disease in a human immunodeficiency virus-negative patient. |
| What to expect beyond the gastric wall. |
| Gut |
| Safety and efficacy of extended surveillance intervals following colorectal endoscopic submucosal dissection: an international multicentre study. |
| Hepatology |
| Seeing the scar in higher resolution: AI-Derived collagen phenotypes redefine fibrosis in MASLD. |
| J Hepatol |
| From the Editor's Desk... |
Letters to the editors and authors’ replies
| Aliment Pharmacol Ther |
|---|
| Editorial: Rifaximin and the Gut-Liver-Brain Axis-Progress and Prudence. Authors' Reply. |
| Editorial: Sleeve Gastrectomy vs. Lifestyle Intervention-Redefining the Therapeutic Hierarchy for Adolescent MASLD? Authors' Reply. |
| Letter on 'Network Meta-Analysis: Comparison of Pharmacological Therapies in Compensated MASH Cirrhosis for Fibrosis Regression and MASH Resolution'. Authors' Reply. |
| Letter: Severity-Informed Enrichment for Recurrent Acute Pancreatitis Trials. Authors' Reply. |
| Letter: Upadacitinib in Perianal Crohn's Disease: Does Clinical Closure Reflect True Remission? Authors' Reply. |
| Clin Gastroenterol Hepatol |
| Optimizing trial design for evaluating combination therapies in IBD. |
| Gastroenterology |
| Two trials with two different answers: potential for Bayesian re-analysis in a Crohn's disease clinical trial. |
| When one trial is not enough: Lessons from darvadstrocel approval and withdrawal. |
| Gastrointest Endosc |
| Caution against aggressive aspiration: reinterpreting risk factors in endoscopic ultrasound-guided through-the-needle biopsy. |
| Challenges and insights in endoscopic full-thickness resection for appendiceal orifice neoplasms. |
| Computed tomography-derived volume of pancreatic fluid collections: promise and practical reporting needs. |
| Concerns regarding the practicality of endoscopic retrograde cholangiopancreatography performed via lumen-apposing gastroenterostomy stent for concomitant gastric outlet and biliary obstruction. |
| Do antimigration stents change outcomes in malignant biliary obstruction? |
| Fluoroscopy-free direct solitary cholangioscopy versus endoscopic retrograde cholangiography for clearance of noncomplex biliary stones: a safety assessment. |
| Improving colorectal polyp size classification with virtual scale endoscopy: implications for resection strategy and surveillance. |
| Making "lifelong biliary drainage" decision-ready: definitions, competing risks, and procedural comparability. |
| No-injection endoscopic submucosal resection by use of a ligation band for small rectal neuroendocrine tumors: improved vertical clearance with important considerations for end point validity and safety. |
| Noninferiority of improved endoscopic mucosal resection versus endoscopic submucosal anatomy for rectal neuroendocrine tumors: insights and future directions. |
| Quantitative recovery assessment after endoscopic submucosal dissection and transanal minimally invasive surgery. |
| Unaddressed confounders in biliary stent occlusion: the impact of neoadjuvant therapy and duodenobiliary reflux. |
| Gut |
| Conclusions in search of a confirmatory analysis: the evidence does not yet justify routine proton pump inhibitors after endoscopic variceal ligation. |
| DR1-DR2 enrichment in HBeAg-negative chronic hepatitis B: integration hotspot or survivor signature? |
| Missing barrier in coeliac disease: why the gut vascular barrier matters. |
| Serum creatinine as both yardstick and predictor: reading chronic kidney disease in the global CLEARED cohort. |
| J Hepatol |
| Quantitative Bias Analysis of Unmeasured Confounding Refines Interpretation of Longitudinal Associations Between Cardiometabolic Risk Factors and Liver Stiffness in MASLD. |
| Redefining Porto-sinusoidal vascular disorder- Is time to move the lens from just diagnosis to a broader picture? |