Fri Apr 24 2026

124 articles - From Friday Apr 17 2026 to Friday Apr 24 2026

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Guidelines

Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…

Gastroenterology
AGA Clinical Practice Update on Risk Stratification and Emerging Surveillance Strategies for Hepatocellular Carcinoma: Expert Review.

However, few scores have undergone sufficient validation to support their use in clinical practice. BEST PRACTICE ADVICE 8: Among patients with chronic hepatitis B virus infection without cirrhosis, PAGE-B and REAL-B scores can stratify patients based on their future risk of hepatocellular carcinoma.

Pubmed   Journal   ReadQx 


Meta-analysis

meta-analyses and systematic reviews

Am J Gastroenterol
Differentiating IgG4-related Sclerosing Cholangitis from Primary Sclerosing Cholangitis: A Comprehensive Systematic Review and Meta-analysis of Diagnostic Features.

Our meta-analysis shows that IgG4-SC and PSC present with similar clinical and radiographic features and possibly comparable histology. A history of unusual pancreatitis and elevated IgG4 (serum or tissue) prompt assessment for more specific radiographic features which if present warrant a therapeutic treatment trial.

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Endosc Int Open
EUS-HGS with antegrade stenting vs. hepaticogastrostomy alone for malignant biliary drainage: Systematic review and meta-analysis.

Combining AS with EUS-HGS reduces RBO risk in patients with MBO, without impact on technical, clinical success rates, or safety profile. Randomized controlled trials are needed to confirm these observations.

Pubmed   Journal   ReadQx   PMC

Endoscopy
Lumen-apposing metal stents vs. self-expandable metal stents for endoscopic ultrasound-guided choledocoduodenostomy: a network meta-analysis of randomized controlled trials.

EUS-CDS with CE-LAMS offers superior procedural efficiency compared with ERCP and SEMS-based approaches with similar clinical success and safety, although concerns about cholangitis warrant further evaluation. Conclusion PROSPERO registration number CRD420251126733.

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Original articles

RCT, clinical trials, retrospective studies, etc…

Aliment Pharmacol Ther
A Care Pathway for the Treatment of IBD Reduces Healthcare Costs and Is Cost-Effective: Results of the Multicentre IBD Value Study.

The implementation of an ACP for the treatment of patients with IBD reduces costs, maintains quality of life and disease control, and is cost-effective. These results emphasise that the implementation of care pathways in current practices should be considered.

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Affinity Proteomics-Based Non-Invasive Detection of Clinically Significant Liver Disease.

We identify a new proteomic score comprising epithelial/hepatic stellate cell markers that yields a robust predictive performance across different liver disease aetiologies. Thereby, we demonstrate the usefulness of emerging proteomic techniques in hepatology.

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Baseline HDV-RNA Levels Could Stratify Clinical Risk Before, But Not After, Cirrhosis in Chronic Hepatitis D: A Multicentre European Study.

Baseline quantitative HDV-RNA allows early risk stratification in untreated patients with chronic hepatitis D before the development of liver cirrhosis. Once cirrhosis is established, clinical outcomes are largely independent of viral replication, emphasising the need to prioritise timely antiviral intervention and close surveillance at earlier disease stages.

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Correlation of Bile Acid Dynamics to Bulevirtide Response and Disease Severity in Patients With Hepatitis D.

Bulevirtide increases bile acid levels in most patients, but ΔBA does not predict virologic response or adverse events, nor does it reflect compliance to therapy. Bile acid level monitoring during and following bulevirtide treatment is thus, not advised for clinical practise.

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Global Longitudinal Assessment of MASLD Using Magnetic Resonance Elastography (GOLDMINE): A Multi-Center, International Prospective Cohort Study of Imaging Biomarkers in MASLD Clinical Outcomes.

GOLDMINE establishes a rigorously phenotyped MASLD cohort integrating centralized histology, advanced MRI-based biomarkers, longitudinal biobanking, and adjudicated outcomes, providing a platform to validate imaging and blood-based prognostic biomarkers in MASLD.

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The Emerging Short Chain Fatty Acid Enriched Metabotype in Irritable Bowel Syndrome and Its Potential Clinical Relevance.

A faecal metabotype enriched in SCFAs associated with an IBS-D phenotype characterised by pain, urgency, rapid transit and higher stool frequency.

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Am J Gastroenterol
Pediatric Versus Adult Colonoscopes Effectiveness in Obese Patients: The PACE Randomized Clinical Trial.

Among expert endoscopists, slim and adult colonoscopes are equivalent in facilitating non-difficult colonoscopy in obese patients, with a trend toward improved performance using the slim colonoscope.

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Sex does not impact the performance of non-invasive tests for clinically significant portal hypertension in cACLD.

Individual noninvasive tests and Baveno VII-based algorithms show a similar accuracy for the diagnosis of CSPH and prognostication in males and females.

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Spontaneous Recovery and Mortality in Patients with ALD Referred for Early Liver Transplantation.

Among patients with ALD and short-term abstinence, BUN and platelets are novel predictors of outcomes, along with INR. Utilizing these predictors - or recalibrating existing MELD coefficients - in this unique patient population may help refine medical selection criteria and improve utility and equity in access to early LT.

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Clin Gastroenterol Hepatol
Germline Variants in Chronic Pancreatitis-associated Genes and Risk of Pancreatic Ductal Adenocarcinoma.

Among CP-associated genes, rare PGVs in PRSS1 and CFTR are associated with PDAC risk. The PRSS1 signal was driven mainly by p.Arg122His, while the CFTR association involved six variants, with five having clinically relevant risk magnitudes. If confirmed in larger studies, these findings could help inform germline testing strategies in patients with PDAC.

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Impact of Chronic Hepatitis B and Its Clinical Phases on Liver Fibrosis and Cirrhosis in MASLD.

Concurrent CHB increased liver fibrosis/cirrhosis risk in MASLD not only in the immune-active phase but also in the grey-zone phase. MASLD patients with concomitant active/grey-zone CHB may warrant enhanced noninvasive monitoring and individualized management to mitigate fibrotic progression.

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Steatotic liver disease, clinical subtypes and adverse perinatal outcomes: the prospective Fatty Liver in Pregnancy Study.

MASLD was frequent among previously undiagnosed individuals during pregnancy. Individualized counseling and pregnancy management based on presence and SLD subtype may aid in optimizing pregnancy outcomes.

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Treatment and Outcomes of Crohn's Disease and Ulcerative Colitis in Newly Diagnosed Adults in the United States, 2007-23.

In a contemporary and diverse cohort of commercially insured adults with newly diagnosed IBD in the U.S., excess corticosteroid use is decreasing in recent era, along with early initiation of advanced therapies. No consistent racial and ethnic, age or sex differences were identified.

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Use of Intestinal Ultrasound in a Tight monitoring approach in Crohn's disease: a multicentre prospective study.

Early IUS evaluation can non-invasively predict treatment outcomes, supporting its integration into tight monitoring protocols for CD. IUS offers a real-time, cost-effective alternative to endoscopy and imaging, potentially enabling timely therapy optimization to improve patient management.

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Endosc Int Open
Application of a novel endoscopic device in treatment of gastric bezoars: Pilot study.

No complications occurred and follow-up gastroscopy confirmed complete bezoar removal with significant symptom improvement. The novel endoscopic device demonstrated high efficacy and safety in treating gastric bezoars, offering a promising alternative to surgical intervention.

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EUS-guided gastroenterostomy for benign gastric outlet obstruction: Clinical and technical outcomes from a multicenter cohort study.

EUS-GE demonstrates high technical and clinical success rates with a favorable safety profile for benign GOO, offering a promising alternative to traditional surgical approaches.

Pubmed   Journal   ReadQx   PMC

Endoloop-assisted endoscopic removal of over-the-scope and full-thickness resection device clips: Prospective study.

Endoloop-assisted removal of OTS and FTRD clips appears to be effective and safe, representing an addition to current options for endoscopic clip removal.

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Exploratory evaluation of magnetic capsule endoscopy with detachable-string for detecting esophageal lesions including early squamous cell carcinoma.

DS-MCCE has potential in detecting early ESCC, mainly for lesions that are larger in size or exhibit pronounced morphological features. These preliminary findings support a further large-sample prospective study and technical refinement.

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Music in complex endoscopy: Effect of functional music on sedation requirements during endoscopic ultrasound and ERCP.

Functional music during complex endoscopic procedures did not reduce propofol consumption but significantly improved satisfaction for both patients and staff. The findings justify implementation of music as a non-pharmacological adjunct to improve patient comfort in endoscopic suites.

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Perioperative low molecular weight heparin bridging in aortic mechanical heart valve patients undergoing endoscopic procedures.

Our findings indicate that although adverse thrombotic events were rare and use of post-procedure LMWH bridging was significantly associated with a small absolute increased risk of bleeding, it was not significant after PSM. Larger prospective studies are needed to better inform antithrombotic management guidelines for patients with aortic MHVs undergoing gastrointestinal endoscopy.

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Quantitative mechanical profiling of 12 ERCP guidewires: Toward evidence-based device selection.

This was the first study to provide integrated mechanical profiles of ERCP and EUS guidewires based on standardized bench-top testing. Radar chart visualization offers an intuitive framework for comparing relative mechanical tendencies and may serve as a useful reference for research and education.

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Real-world practices and barriers in endoscopic submucosal dissection training: International comprehensive survey.

This international survey reveals substantial disparities in ESD training and calls for coordinated efforts to improve access to structured curricula, mentorship, and affordable training models.

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Reliability and utility of the Toronto Upper Gastrointestinal Cleaning Score for optimizing mucosal visualization during esophagogastroduodenoscopy.

TUGCS is a reliable and reproducible tool across varying levels of endoscopic expertise. Higher scores were associated with improved detection of gastroduodenal pathology, supporting its utility as a quality metric in EGD. Multicenter studies are warranted to validate its role in broader clinical practice.

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Through-the-scope clip with anchor prongs for defect closure following myotomy, resection, anti-reflux mucosectomy, fistula management, or bleeding.

The newly designed TTSC with anchor prongs demonstrated safety and efficacy in defect closures after submucosal interventions, with high rates of successful defect closure and no delayed bleeding. (ClinicalTrials.gov number, NCT05653843).

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Use of rebamipide solution as a submucosal injection material to prevent esophageal stricture after endoscopic submucosal dissection: Animal study.

The rebamipide solution showed no statistically significant benefit in preventing post-ESD stricture. However, given the small sample size of this study, further studies are needed to clarify its potential role.

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Endoscopy
Effectiveness and safety of ERCP using the European Society of Gastrointestinal Endoscopy algorithm for biliary cannulation: a prospective study.

Adherence to the ESGE cannulation algorithm was feasible and was associated with higher cannulation success during ERCP.

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Gastroenterology
Achalasia and risk of esophageal squamous cell carcinoma and adenocarcinoma in a multinational study.

Achalasia appears strongly and independently associated with esophageal squamous cell carcinoma. The association with esophageal adenocarcinoma is less strong and seems to be largely explained by GERD.

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CLONAL LYMPHOCYTE EXPANSIONS AND JAK-STAT PATHWAY MUTATIONS DEFINE A PATHOGENIC CONTINUUM DRIVING RESISTANCE TO GLUTEN-FREE DIET IN CELIAC DISEASE.

These findings suggest that RCD subtypes may share underlying mechanisms driven by clonal evolution and JAK-STAT dysregulation. They also highlight the potential limitations of JAK inhibitor monotherapy and the importance of molecularly informed therapeutic strategies.

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Pre-Crohn's Disease Stool from Discordant Siblings Promotes the Development of Colitis in Germ-Free Mice.

This study functionally demonstrates that the stool microbiome of individuals susceptible to CD is altered years before diagnosis, exhibiting greater inflammatory potential when transferred to susceptible mice.

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Protein misfolding enteropathy predicts and prognosticates neurodegenerative disease years before symptom onset.

Our findings reveal that neurodegeneration-associated proteinopathies are not confined to the central nervous system but can be detected in routine GI biopsies years before clinical onset. This discovery provides a practical and scalable biomarker platform that could transform early diagnosis, risk stratification, and target-engagement monitoring in clinical trials. Protein misfolding enteropathy represents a new frontier for disease interception in neurodegenerative disorders, enabling intervention at a stage when neuronal damage may still be preventable.

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Gastrointest Endosc
Blown-out myotomy after peroral endoscopic myotomy: incidence, clinical impact, and procedural factors in a large single-center cohort.

BOM is an uncommon but clinically important structural complication after POEM, with a low incidence of 1.9% in this large single-center cohort. Although no clear procedural risk factors were identified, and time-to-event analyses did not reveal consistent predictors, the presence of BOM was associated with worse clinical outcomes. Continued attention to procedural quality may help minimize its occurrence and improve long-term outcomes after POEM.

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Contractility patterns on functional lumen imaging probe prior to peroral endoscopic myotomy predict outcomes in achalasia.

Absent CR on FLIP prior to POEM predicts significant barium retention on TBE following POEM, supporting an additive diagnostic role for FLIP in achalasia therapeutic outcome predictions.

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Endoscopic Ultrasound-Assisted Gastric Outlet Remodeling Using Parallel Lumen-Apposing Metal Stents and Septotomy: A Human Feasibility Study.

EUS-GOR is technically feasible, safe and clinically effective in patients with refractory GJ strictures post-RYGB. This technique may offer a minimally invasive alternative to surgical revision in high-risk patients.

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Indeterminate Main Pancreatic Duct Dilation: An Endoscopic Ultrasound-Based Machine Learning Model to Distinguish Main Duct-Intraductal Papillary Mucinous Neoplasm from Chronic Pancreatitis.

An interpretable EUS-based machine learning model differentiates MD-IPMN from CP-associated duct dilation, including stone-negative cases, and may support standardized evaluation when cross-sectional imaging is inconclusive.

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Linked color imaging with computer-aided detection and the proximal adenoma miss rate: a randomized tandem trial.

Compared to conventional colonoscopy, LCI with CADe colonoscopy resulted in a statistically significant decrease especially in AMR. (UMIN 000050685).

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Real-World Outcomes of Duodenal Endoscopic Submucosal Dissection and Endoscopic Full-thickness Resection: Predictors of Adverse Events and the Role of a Structured Closure Approach (with video).

ESD and EFTR are effective and safe for selected duodenal lesions. Severe fibrosis, especially with ulceration, predicted procedural complications in SEL. A structured closure strategy helped minimize delayed adverse events.

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Gut
Circulating extracellular vesicle long RNA profiling combined with machine learning unveils novel diagnostic signature and molecular features in chronic pancreatitis.

Our study is the first to report an ExLRs-based diagnostic model that demonstrates exceptional robustness in differentiating CP from healthy controls and non-pancreatic disease controls. ExLRs offer a promising tool for CP molecular characterisation and pathophysiological quantification.

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Norepinephrine promotes tumour cell aggressiveness and NK cell ferroptosis via ADRB2 in intrahepatic cholangiocarcinoma with perineural invasion.

This study uncovers a novel neuro-immune-tumour axis in iCCA and provides a mechanistic rationale for targeting β-adrenergic signalling as a possible therapeutic strategy for PNI + iCCA.

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Hepatology
Development and validation of risk stratification models for hepatocellular cancer: A framework from the translational liver cancer consortium.

The group also defined a set of recommendations to improve the rigor of development and validation of HCC risk stratification strategies. This framework can inform best practices and highlight necessary steps for endorsement by practice guidelines and regulatory agencies, highlighting a path toward implementation in clinical practice.

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J Hepatol
Fusobacterium nucleatum alleviates alcohol-associated liver disease through mannose-mediated elevation of Fbp1 and modulation of gut microbiota.

This study identifies F. nucleatum as a commensal with hepatoprotective effects in ALD, acting through a mannose-Fbp1 signaling axis and gut microbiota modulation. These findings highlight mannose as a microbiota-derived therapeutic candidate and suggest that targeting bacterial metabolites, rather than liver bacterial administration, may represent a promising strategy for ALD intervention.

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Single-nucleus profiling reveals hepatocyte identity and immune features associated with corticosteroid response in severe alcohol-related hepatitis.

This study delineates distinct immune and hepatocyte changes associated with corticosteroid response in sAH. Baseline SULT2A1 expression may facilitate stratified treatment approaches in sAH. Impact and implications Severe alcohol-related hepatitis (sAH) represents one of the most devastating manifestations of alcohol-related disorders. sAH is characterized by acute hepatic inflammation and high short-term mortality. Clinical management remains challenging, as corticosteroids - the only pharmacological therapy currently applied - are ineffective in a substantial proportion of patients and are associated with significant adverse effects. These limitations highlight the need for a more detailed understanding of sAH pathophysiology and for approaches that enable improved patient stratification and therapeutic decision-making. In this study, we identify distinct pre-treatment differences between corticosteroid responders and non-responders at the level of both hepatocytes and myeloid cells, providing new insight into the cellular mechanisms underlying treatment heterogeneity in sAH. Furthermore, leveraging these findings, we developed a histology-based SULT2A1 scoring system using a commercially available antibody, which predicts corticosteroid response at baseline and may support stratified treatment approaches in clinical practice.

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Vitamin B6 predicts poor outcomes in geographically distinct populations with primary sclerosing cholangitis.

Vitamin B6 deficiency was common in PSC also outside Scandinavia and consistently associated with poor outcomes in geographically distinct PSC populations. Impact and implications We previously showed that vitamin B6 deficiency was prevalent and associated with reduced liver transplantation-free survival in Scandinavian PSC cohorts. The current work shows that these observations are translatable to a U.S population and that low vitamin B6 also associates with development of hepatic decompensation. Our findings show that vitamin B6 adds value to predict outcomes in PSC across geographically distinct PSC populations and that efforts to restore B6 sufficiency should be focused on the many individuals who present with vitamin B6 levels within the marginal-to-definitive deficiency range.

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link

Aliment Pharmacol Ther
Editorial: The Milan Score as Supportive Evidence of Gastro-Oesophageal Reflux Disease.

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Editorial: The Role of Liver Biopsy in ANA Positive Subjects.

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Editorial: Using HBcrAg and HBsAg Kinetics to Optimise Monitoring After Nucleo(s)tide Analogue Withdrawal.

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Gastroenterology
Gastrointestinal Disorders in Scleroderma.

High-quality SSc-specific evidence regarding the impact of various therapies on GI manifestations remains limited, and management recommendations for most GI manifestations are largely derived from experience in non-SSc patients. In caring for the SSc patient with GI problems a gastroenterologist should be aware of the particularities of clinical presentation and natural history of GI disease in this patient population, maintain diagnostic vigilance and tailor their therapeutic approach mindful of the SSc disease process.

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Gut
Gastric microbiota-mediated immune remodelling in gastric cancer.

We conclude by highlighting current challenges and providing future directions for microbiota research in GC. Overall, a deeper understanding of host-microbe interactions can provide promising avenues for precision medicine and the development of microbiota-targeting interventions against GC.

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J Hepatol
Beyond proliferation: YAP shapes the tumor identity and immune landscape of intrahepatic cholangiocarcinoma.

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Peeling back the layers: resident Kupffer cell plasticity shapes hepatic defense lines in tuberculosis granulomas.

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Precision oncology in primary liver cancer: bridging the gap between molecular profiling and patient benefit.

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The Illusion of Harmonisation in ACLF.

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Miscellaneous

misc publications eg case reports, tools of the trade, images of the month, etc…

Am J Gastroenterol
Challenging the Paradigm a Symptom-Based Classification Is Sufficient for Identifying Disorders of Gut-Brain Interaction.

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Choledochoscope removal of a sharp appendiceal foreign body.

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HOW WE APPROACH IT: REPORTING ESOPHAGEAL MANOMETRY FINDINGS.

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Post-Stroke Oropharyngeal Dysphagia: A Clinical Approach to Diagnosis and Management.

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Response to Rex and Guardiola.

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Severe Melanosis Coli Associated With Chronic Aloe Vera Supplement Use.

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Clin Gastroenterol Hepatol
Intestinal inflammation impacts gestational weight gain in women with inflammatory bowel disease and growth in offspring.

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UNSEDATED TRANSNASAL ESOPHAGOGASTRODUODENOSCOPY FOR EVALUATION OF CELIAC DISEASE.

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Endosc Int Open
Successful endoscopic sphincterotomy using a rotatable sphincterotome in a patient with situs inversus totalis.

Pubmed   Journal   ReadQx   PMC

Endoscopy
A case of gas in the stomach wall and portal vein following endoscopic ultrasound-guided hepaticogastrostomy.

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A novel "twist-and-drag" loop clip technique for closure of mucosal defects after colorectal endoscopic submucosal dissection.

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A novel endoscopic capsule sponge-based technique called transendoscopic sampling for early detection and risk stratification in Barrett's neoplasia.

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An endoscopic triumph: transgastric balloon-anchored antegrade dilation via gastrostomy reopens a "no-pass" esophagus.

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Benefit of multi-hole self-expandable metal stent placement for hilar biliary bleeding: effective hemostasis without biliary branch obstruction.

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Cancer risk in gastric hyperplastic polyps: mucosal context rather than polyp features?

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Colonoscopy report generation using voice recognition system.

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Commentary on "Single-use versus reusable gastroscopes for the initial assessment of patients with upper gastrointestinal bleeding".

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Complete closure of an ileal perforation during enteroscopy using a novel through-the-scope twin clip.

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Endoscopic closure of an esophago-bronchial fistula after esophageal atresia repair using autologous adipose stromal vascular fraction and platelet-rich plasma injection.

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Endoscopic resection as a "resect-to-confirm" strategy after neoadjuvant downstaging for remnant gastric cancer.

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Endoscopic submucosal tunnel implantation of sodium hyaluronate for gastroesophageal reflux disease: a pilot survival porcine study.

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Endoscopic transgastric removal of a migrated intrahepatic fish bone via a cardia-lesser curvature tunnel.

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Endoscopic ultrasound localisation of completely embedded oesophageal fish bone and endoscopic retrieval.

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Endoscopic ultrasound-guided biliary drainage after failed ERCP: are we ready for definitive conclusions?

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Endoscopic ultrasound-guided hepaticogastrostomy with antegrade and bridging stenting for diffusely extending cholangiocarcinoma.

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Endoscopy E-Videos - recently published.

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Inward migration of a dedicated hepaticogastrostomy plastic stent into the bile duct after hepaticojejunostomy.

Pubmed   Journal   ReadQx   PMC

Is accurate withdrawal time measurement enough in colonoscopy? The next step for computer-aided quality assurance.

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Management of afferent loop syndrome with a second endoscopic ultrasound-guided gastrojejunostomy in advanced cholangiocarcinoma.

Pubmed   Journal   ReadQx   PMC

Massive iatrogenic duodenal deficiency: originating from and resolved by endoscopic treatment.

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Misdeployment of the metal stent during direct endoscopic ultrasound-guided hepaticogastrostomy without tract dilation.

Pubmed   Journal   ReadQx   PMC

Multi-hole two-way hybrid placement using three 8-mm metal stents for malignant hilar biliary obstruction.

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Multicenter validation of cholangioscopy artificial intelligence: considerations for generalizability and clinical implementation.

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Percutaneous endoscopic necrosectomy using a novel slim gastroscope with a large working channel for pancreatic walled-off necrosis.

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Stent-free biliary bypass by endoscopic ultrasound-guided choledochoduodenostomy for benign common hepatic duct stricture.

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Successful removal of a migrated duodenal-jejunal bypass liner from deep jejunum via single-balloon enteroscopy.

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Gastroenterology
An Unexpectedly Rare Adverse Event of EUS-Guided Celiac Plexus Block.

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It's Hard to Swallow: Using Histology When Endoscopy Fails.

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Multi-center Prospective Evidence of Kidney Safety of NSAIDs for Prevention of Post-ERCP Pancreatitis.

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Patient-Inclusive Recruitment in Inflammatory Bowel Disease Trials: Key Takeaways From the 2025 Strategic Alliance for Intercultural Advocacy in GI-American Gastroenterological Association Asian Clinical Research Roundtable.

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Gastrointest Endosc
Choledocho-duodenal Fistula Induced by a Forgotten Plastic Biliary Stent Retained for 10 Years.

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Closure of a large post-ESD rectal perforation with multiple over-the-scope clips.

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Varioliform Gastric Metastasis from Invasive Ductal Breast Carcinoma.

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Gut
CD48<sup>+</sup> tumour-associated macrophages: novel immunotherapeutic targets in hepatocellular carcinoma.

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Hepatology
Beyond clinical comorbidities: Social determinants of health shape cirrhosis risk.

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Retraction: Capn4 overexpression underlies tumor invasion and metastasis after liver transplantation for hepatocellular carcinoma.

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Survival in de novo perihilar cholangiocarcinoma: Does transplant outperform resection?

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The hitchhiker's guide to personalized immunotherapy: How tertiary lymphoid structures predict adjuvant treatment success in HCC.

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When the liver loses its zip code: Aging blurs zonation and breeds bi-zonal hepatocytes.

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J Hepatol
Assembling a new model to interrogate human liver biliary diseases.

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From the Editor's Desk...

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Letters&Replies

Letters to the editors and authors’ replies

Aliment Pharmacol Ther
Editorial: Gene Silencing Therapy for a New Era of Pancreatitis Prevention. Authors' Reply.

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Letter: Are All Extra-Digestive Cancer Signals in Inflammatory Bowel Disease Telling the Same Story? Authors' Reply.

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Letter: Beyond Survival Benefit in CHANCE2311-Important Considerations in the Interpretation of TACE Combined With Immunotherapy in Advanced HCC.

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Letter: Beyond the Mucosa-Strengthening the Case for Transmural Healing as a Monitoring Target in Crohn's Disease.

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Letter: Incremental Value and Stratified Interpretation of Dual Autoantibody Positivity in Primary Biliary Cholangitis. Authors' Reply.

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Letter: Reconsidering Tenofovir Disoproxil Fumarate Use in Light of Emerging Safety Evidence.

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Letter: The Persistence of Anxiety and Depression in Inflammatory Bowel Disease-A Core Phenotype Beyond Inflammatory Activity. Authors' Reply.

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Letter: Unmasking the Risks-The Need for Robust Data on Baclofen in Cirrhotic Patients.

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Clin Gastroenterol Hepatol
Beyond Morphology: Influence of Stent Caliber and Indication on the Efficacy of Lumen-Apposing Metal Stents with Coaxial Pigtails.

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Response to Takahashi ('Beyond Morphology: Influence of Stent Caliber and Indication on the Efficacy of Lumen-Apposing Metal Stents with Coaxial Pigtails').

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Endosc Int Open
Comment on the study by Fukuya et al. (2025).

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Gastroenterology
Confounding of sex-biased gene expression in Crohn's disease recurrence.

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Gut
Letter to the editor regarding: Lai, Jimmy Che-To, et al "Non-invasive risk-based surveillance of hepatocellular carcinoma in patients with metabolic dysfunction-associated steatotic liver disease".

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Offspring MASLD risk and the shared familial metabolic milieu: beyond intrauterine explanation.

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Universal ESD for Barrett's neoplasia: the T1b '"limbo'" and risk of overtreatment.

Pubmed   Journal   ReadQx 

J Hepatol
Authors' Reply: Not yet time to A-Tango in redefining acute-on-chronic liver failure.

Pubmed   Journal   ReadQx 

Primary sclerosing cholangitis: time to rethink imaging criteria for early disease detection.

Pubmed   Journal   ReadQx 

Single-nucleus and spatial transcriptomic analyses reveal intra-tissue heterogeneity of PNPLA3.

Pubmed   Journal   ReadQx