Fri Apr 17 2026

134 articles - From Friday Apr 10 2026 to Friday Apr 17 2026

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Guidelines

Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…

Clin Gastroenterol Hepatol
Updated Global Consensus Recommendations for Risk Stratification, Treatment Initiation, and Response Monitoring in Metabolic Dysfunction-Associated Steatotic Liver Disease.

This updated international consensus provides practical algorithms that integrate noninvasive testing with recently approved pharmacologic therapies for MASLD, addressing current variability in clinical practice and supporting standardized implementation of risk-based care.

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Meta-analysis

meta-analyses and systematic reviews

Am J Gastroenterol
Differentiating IgG4-related Sclerosing Cholangitis from Primary Sclerosing Cholangitis: A Comprehensive Systematic Review and Meta-analysis of Diagnostic Features.

Our meta-analysis shows that IgG4-SC and PSC present with similar clinical and radiographic features and possibly comparable histology. A history of unusual pancreatitis and elevated IgG4 (serum or tissue) prompt assessment for more specific radiographic features which if present warrant a therapeutic treatment trial.

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Clin Gastroenterol Hepatol
Efficacy of Biological and Steroid Therapies in Adolescent and Adult Patients with Eosinophilic Esophagitis: A Systematic Review and Network Meta-Analysis with Meta-regression.

All evaluated therapies except etrasimod achieved histologic remission, while only dupilumab, cendakimab, BOS, and BOT were associated with symptomatic improvement in EoE, highlighting dissociations between histologic and symptomatic responses. Most corticosteroid trials were short-term and lacked direct comparisons with biologics. Robust head-to-head trials are needed to define optimal treatment strategies, assess long-term outcomes, and clarify the role of symptom, endoscopic, and histologic endpoints in therapeutic decision-making.

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Global incidence, prevalence, and risk factors of microscopic colitis, 1984-2020: a systematic review and meta-analysis.

This study offers updated global estimates of MC burden, noting recent regional trends. Observed heterogeneity and geographic variation highlight the need for further research into hormonal and environmental risk factors.

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Endosc Int Open
EUS-HGS with antegrade stenting vs. hepaticogastrostomy alone for malignant biliary drainage: Systematic review and meta-analysis.

Combining AS with EUS-HGS reduces RBO risk in patients with MBO, without impact on technical, clinical success rates, or safety profile. Randomized controlled trials are needed to confirm these observations.

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Original articles

RCT, clinical trials, retrospective studies, etc…

Aliment Pharmacol Ther
A Nationwide Assessment of Anticholestatic Therapy Uptake in Patients With Primary Biliary Cholangitis: Opportunities for Optimisation.

During recent years, UDCA was insufficiently dosed in Dutch patients with PBC. The results indicate that first-line treatment can be optimized, especially in those with a biochemical response and higher body weight.

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Diagnostic Impact of Liver Biopsy Among Antinuclear Antibody Positive Individuals With Mild Liver Enzyme Elevation.

Liver biopsy provides limited additional diagnostic value in ANA-positive, non-cirrhotic patients with alanine aminotransferase < 101 U/L and no alternative suspected aetiology. In such cases, the procedure can be safely deferred, reserving biopsy for higher enzyme elevations or unclear differential diagnoses.

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Validation of the Milan Score Using Prolonged Wireless PH Monitoring.

Abnormal Milan Score reliably predicts pathologic reflux per Lyon Consensus 2.0 on 96-h wireless pH-monitoring, with performance similar to 24-h pH-impedance. This validation strengthens evidence for the Milan Score in GERD diagnosis.

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Am J Gastroenterol
Association of Body Mass Index with Disorders of Gut-Brain Interaction: A Large Global Population-Based Analysis.

Higher, but not lower, BMI is independently associated with increased prevalence and symptom burden of DGBI. Obesity confers the highest odds for overlapping disorders and psychological disturbances, underscoring the importance of integrated metabolic and behavioral management strategies.

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Patient Preferences in Hepatocellular Carcinoma Surveillance: A Multi-site Conjoint Analysis.

Patients with undergoing HCC surveillance prioritize surveillance test sensitivity; however, results vary by race, ethnicity, and SES. Improving access by reducing financial and logistical barriers through shared-decision-making may enhance surveillance, particularly when modalities present with similar effectiveness.

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Clin Gastroenterol Hepatol
A MACHINE-BASED LEARNING MODEL FOR RECURRENCE PREDICTION AND TIMING AFTER ENDOSCOPIC ERADICATION THERAPY FOR BARRETT'S ESOPHAGUS.

This US-based externally validated tool accurately predicts BE and BE-related neoplasia recurrence and timing post EET. This practical tool may help provide a personalized approach to surveillance strategies.

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Classification of biliary strictures using real-time cholangioscopy artificial intelligence: the SMART-AI trial.

This trial demonstrates that sampling techniques and human assessment of biliary strictures are flawed and there may be a benefit to the use of a cholangioscopy AI system to aid in biliary stricture classification.

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Decreasing primary resection rates for Crohn's disease but unchanged re-resection rates: A nationwide Danish population-based cohort study from 1997 to 2021.

Rates of primary resections in CD have decreased over the past decades without any evidence that this has been achieved at the expense of increased complexity at surgery. Re-resection rates have not changed the past decades, suggesting a potential for improvement.

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Effect of diet and enteral tube type on gastric bile acid concentrations and relationship with pulmonary outcomes.

For patients at high risk for bile acid related aerodigestive complications, tube and diet type may affect gastric bile acid concentrations, in turn impacting important clinical outcomes of hospitalization rates and airway inflammation.

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Endosc Int Open
Adverse events associated with full-thickness resection devices in gastrointestinal endoscopy: National postmarketing surveillance study.

EFTR with FTRD is associated with device malfunctions and patient complications, with colonic perforation being the most frequently reported complication. Careful patient selection and procedural expertise are critical to reduce risk.

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Delayed surveillance colonoscopy after piecemeal EMR is not associated with increased recurrence rates.

Delayed SC1 is not associated with increased recurrence rates. Complete resection can be anticipated for most lesions and SC1 at 1-year post resection may be sufficient.

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Development of a national root cause analysis system for post-endoscopy upper gastrointestinal cancer.

A process to identify PEUGIC across a national healthcare system and to perform root cause analysis is described. The methodology is transferable to other healthcare systems with large national datasets, but even without such datasets, the root cause analysis process developed allows identification of learning from PEUGIC for local endoscopy quality improvement.

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Diagnostic value of non-magnifying gastroscopy followed by targeted biopsy for detection of early gastric cancer: Multicenter prospective study.

Targeted biopsy of suspicious lesions for HGN with non-magnifying gastroscopy can be used as a primary clue for detecting EGC.

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Durable endoscopic gastrojejunal anastomosis using the double-lumen apposing metal stent septotomy technique: Feasibility study.

The double LAMS septotomy technique is technically feasible, safe, and achieves durable gastrojejunostomy. This strategy may broaden the therapeutic role of EUS-GE in benign disease.

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EUS-guided gastroenterostomy for benign gastric outlet obstruction: Clinical and technical outcomes from a multicenter cohort study.

EUS-GE demonstrates high technical and clinical success rates with a favorable safety profile for benign GOO, offering a promising alternative to traditional surgical approaches.

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Endoloop-assisted endoscopic removal of over-the-scope and full-thickness resection device clips: Prospective study.

Endoloop-assisted removal of OTS and FTRD clips appears to be effective and safe, representing an addition to current options for endoscopic clip removal.

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Endoscopic sleeve gastroplasty: Prospective assessment of weight loss and metabolic impact.

ESG combined with LSM resulted in significant improvement in TBWL, EWL, BMI, and QoL. Metabolic improvements were also observed without leading to nutritional deficiency.

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Endoscopic ultrasound-guided transgastric drainage of pancreaticopleural fistulas.

EUS-guided transgastric drainage appears to be a promising alternative for refractory PPF, resulting in technical and clinical success with minimal AEs. Long-term follow-up underscores sustained symptom resolution and absence of recurrence, highlighting its potential in managing this challenging complication.

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Esophageal myotomy and risk of esophageal cancer and mortality in achalasia: Real-world cohort study.

In short-term follow-up, esophageal myotomy in achalasia was associated with lower all-cause mortality and similar esophageal cancer incidence. These findings suggest benefits beyond symptom control, including a potential survival advantage.

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Evaluation of time to endosonographic creation route after endoscopic ultrasound-guided hepaticogastrostomy.

In conclusion, ESCR may have been established by a median of 13 days following EUS-HGS using SEMS; however, time to ESCR formation should be evaluated in a future study.

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Gravity-sensing device for measuring bending angles in digestive endoscopes: Design and clinical evaluation.

This single-operator tool utilizes a freely rolling ball bearing within a calibrated ring to quantify angles. A multicenter instrument comparison demonstrated that the device significantly improved measurement efficiency and consistency while reducing associated maintenance costs, offering a practical solution for endoscopy unit quality control.

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Impact of acetic acid chromoendoscopy on detection of serrated lesions in the proximal colon compared with white-light endoscopy.

HD-WLE with sequential application of 2% acetic acid chromoendoscopy was associated with higher proximal SL detection compared with HD-WLE alone. Hypertension was the only risk factor significantly associated with proximal SL detection, within the context of a sequential examination design.

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Music in complex endoscopy: Effect of functional music on sedation requirements during endoscopic ultrasound and ERCP.

Functional music during complex endoscopic procedures did not reduce propofol consumption but significantly improved satisfaction for both patients and staff. The findings justify implementation of music as a non-pharmacological adjunct to improve patient comfort in endoscopic suites.

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Octreotide for prevention of delayed bleeding after endoscopic mucosal resection for large superficial non-ampullary duodenal tumors.

In this exploratory study, postprocedural intravenous octreotide appeared to be associated with a lower occurrence of DB after EMR for large SNADTs (≥ 30 mm). Larger, prospective studies are warranted to confirm these findings.

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Precision vs. cost: Endoscopic ultrasound-guided vs. conventional pancreatic cyst drainage in a resource-limited setting.

EUS-guided and conventional transgastric drainage demonstrate comparable safety and efficacy. In resource-limited settings, CTG remains a cost-effective option in appropriately selected patients.

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Quantitative mechanical profiling of 12 ERCP guidewires: Toward evidence-based device selection.

This was the first study to provide integrated mechanical profiles of ERCP and EUS guidewires based on standardized bench-top testing. Radar chart visualization offers an intuitive framework for comparing relative mechanical tendencies and may serve as a useful reference for research and education.

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Real-world practices and barriers in endoscopic submucosal dissection training: International comprehensive survey.

This international survey reveals substantial disparities in ESD training and calls for coordinated efforts to improve access to structured curricula, mentorship, and affordable training models.

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Reliability and utility of the Toronto Upper Gastrointestinal Cleaning Score for optimizing mucosal visualization during esophagogastroduodenoscopy.

TUGCS is a reliable and reproducible tool across varying levels of endoscopic expertise. Higher scores were associated with improved detection of gastroduodenal pathology, supporting its utility as a quality metric in EGD. Multicenter studies are warranted to validate its role in broader clinical practice.

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Self-assembling peptide hydrogel prevents esophageal stenosis after endoscopic submucosal dissection for esophageal squamous cell carcinoma: Multicenter prospective study.

PuraStat application for post-endoscopic submucosal dissection ulcers in patients with ESCC may be useful for preventing esophageal stenosis.

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Technical & clinical evaluation of a novel slim gastroscope in third-space procedures: Feasibility, subjective workload & system usability assessment.

A novel slim gastroscope offers high usability with a low subjective workload for third space procedures. The slim gastroscope has the potential to reduce ergonomic strain on endoscopists during complex therapeutic interventions.

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Temporary sphincter-preserving covered biliary stent with a frontal umbrella-shaped occlusive mechanism for common bile duct stone removal.

In summary, this preliminary study demonstrates the safety and feasibility of TSP-CBS for performing EST-free ERCP in patients with CBD stones. Further validation in larger clinical cohorts is warranted.

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Through the scope, not the ceiling: Gender distribution among endoscopy sessions at the German Visceral Medicine Congress.

In 2019, the German Society of Gastroenterology, Digestive and Metabolic Diseases Board introduced a parity resolution concerning gender balance among congress session chairs. Since then, notable progress towards achieving gender parity has been made, with a positive trend being indicative of effectiveness of current DEI measures. Nevertheless, there remains a significant lack of adequate female representation in endoscopy sessions, particularly among central congress formats and among speakers. To address this imbalance, further measures such as binding quotas, institutional support, and targeted diversity-oriented congress planning are necessary.

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Through-the-scope clip with anchor prongs for defect closure following myotomy, resection, anti-reflux mucosectomy, fistula management, or bleeding.

The newly designed TTSC with anchor prongs demonstrated safety and efficacy in defect closures after submucosal interventions, with high rates of successful defect closure and no delayed bleeding. (ClinicalTrials.gov number, NCT05653843).

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Uncovered versus fully-covered self-expandable metal stents for nonpancreatic cancer: Propensity score-matched, multicenter study.

UCSEMS may be safer than FCSEMS for managing dMBO caused by nonpancreatic cancer.

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Gut
<i>Bifidobacterium catenulatum</i> boosts anti-PD-1 efficacy in microsatellite stable colorectal cancer via activating CD8<sup>+</sup> T cells.

Design The abundance of bacteria in CRC patients was evaluated in our in-house cohorts and validated in published datasets. The effect of candidate bacterium with anti-PD-1 therapy was determined in two syngeneic mouse models of MC38 (microsatellite instability-high) and CT26 (microsatellite stable, MSS), transgenic is a potential adjuvant to improve immunotherapy against CRC.

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<i>Tff2</i> marks gastric corpus progenitors that give rise to pyloric metaplasia/SPEM following injury.

Tff2 + corpus progenitors represent a common cellular origin for SPEM and gastric dysplasia, challenge the conventional stepwise model of gastric carcinogenesis and indicate divergent differentiation programmes from Tff2 + progenitors.

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CD16<sup>+</sup> γδ T cells mediate antibody-dependent cellular cytotoxicity and associate with viral control in chronic hepatitis B virus infection.

CD16 + γδ T cells mediate antibody-dependent antiviral immunity in HBV infection. Their inverse association with HBcrAg links γδ T cell-mediated ADCC to viral control and highlights this pathway as a target for HBV cure strategies.

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Quantifying artificial sweeteners and emulsifiers in Crohn's disease and its relationship with disease activity: the ENIGMA study - a novel and targeted approach.

This is the first human study to demonstrate distinct P-80 metabolism in patients with CD compared with controls. Dietary sweeteners and P-80 metabolites showed significant correlations with disease activity, suggesting their potential utility as non-invasive biomarkers for CD activity assessment.

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RNA binding protein CAPRIN1 suppresses STAT1 translation and interferon signalling to promote HBV replication.

CAPRIN1 is elevated in IFN non-responders and further upregulated during HBV infection/replication. By facilitating stress granule formation and stabilising STAT1 rG4 structure, CAPRIN1 blocks ribosomal scanning and suppresses STAT1 translation. We therefore designate CAPRIN1 as a critical rheostat that calibrates the amplitude of IFN responses during innate immunity and adjuvant IFN-α therapy.

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Stromal biomarker-based framework for identifying pMMR/MSS and dMMR/MSI colorectal cancers with poor outcomes and limited benefit from immunotherapy.

CTHRC1-expressing CAFs represent clinically relevant biomarkers that link molecular profiling with diagnostic pathology. Our findings support the potential incorporation of CTHRC1(+) CAF assessment into routine histopathological workflows, pending prospective validation, and suggest a framework for stroma-informed CRC stratification, particularly in patients with stroma-rich, treatment-resistant tumours and pMMR/MSS with limited therapeutic options.

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Targeting PKM2-dependent glycolysis reprogrammes monocytes into Cadm1<sup>+</sup> macrophages to promote mucosal repair and attenuate colitis progression.

Therapeutic targeting of PKM2-dependent glycolysis in macrophages enhanced Cadm1 + macrophage-mediated mucosal healing without driving tumourigenesis.

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Tryptophan depletion generates hyper-reactive portal neutrophils in alcoholic liver disease.

Our findings identify portal tryptophan as a local regulator of neutrophil activation in ACLD. The link between low tryptophan levels and heightened neutrophil reactivity, especially in ALD, underscores the role of the gut-liver metabolic crosstalk in immune modulation and highlights a potential therapeutic target for mitigating neutrophil-driven liver injury.

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Hepatology
Genetic risk of steatotic liver disease: Pathogenesis, prognosis, and implications for treatment.

In addition, genetic studies have paved the way for the development of several targeted therapies. Here, we review the major insights into SLD pathogenesis gleaned from over 20 years of human genetic studies, and their implications for the treatment and prevention of SLD.

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Toxic lipid-induced epigenetic activation of ICAM1 in liver sinusoidal endothelium regulates myeloid-driven fibro-inflammatory response in MASH.

ICAM1 is epigenetically upregulated in LSECs during lipotoxic stress and promotes myeloid cell recruitment in MASH. Targeting the epigenetic regulation of ICAM1 may offer a novel therapeutic strategy for treating human MASH.

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J Hepatol
144 Weeks of bulevirtide monotherapy for chronic hepatitis D: Final and posttreatment results from a Phase 3 randomized trial.

Bulevirtide treatment for CHD for up to 144W was safe and effective. Response rates decreased after treatment discontinuation; however, some patients had sustained undetectable HDV RNA throughout 2 years of follow-up. (Funded by Gilead Sciences; MYR301 ClinicalTrials.gov number, NCT03852719). Impact and implications Although bulevirtide is approved for treatment of chronic hepatitis D (CHD) in the European Economic Area, the United Kingdom, Switzerland, the Russian Federation, Australia, and Canada, treatment outcomes beyond 2 years and after bulevirtide discontinuation remain unknown. In this analysis, we demonstrate that efficacy was maintained with bulevirtide monotherapy for up to 144 weeks compared with that at 96 weeks, while rates of HDV RNA undetectability continued to improve with extended treatment duration. Virologic and biochemical responses decreased after treatment discontinuation, but some patients who were undetectable at EOT maintained HDV RNA undetectability posttreatment, with duration of continuous HDV RNA undetectability at EOT being the strongest predictor of non-relapse. While most patients benefit from continued bulevirtide therapy, a subset of those who achieve undetectable HDV RNA may be able to discontinue treatment without loss of response even in the absence of HBsAg loss. Clinical trial number NCT03852719.

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J Neurogastroenterol Motil
Belching and Reflux: The Relationship and the Underlying Mechanism.

This study demonstrated that belching might trigger reflux by increasing intragastric pressure, elevating the gastric-sphincter pressure gradient, which enables gastric contents to pass through the esophagogastric junction. These findings have crucial clinical significance, suggesting that reducing the occurrence of belching might be a potential treatment for refractory reflux.

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Clinical Outcomes of Endoscopic Radiofrequency Stretta Therapy for Gastroesophageal Reflux Disease Treatment: A Retrospective Analysis From 2 Tertiary Centers in Korea.

Endoscopic radiofrequency Stretta therapy appears to be a safe treatment option for GERD and may provide favorable patient satisfaction and medication reduction.

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DA-9701 for Gastrointestinal Symptoms in Postural Orthostatic Tachycardia Syndrome: A Randomized Pilot Study.

DA-9701 did not improve GI symptoms in this crossover trial; however, its potential effect on specific GI symptoms merits further investigation.

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Dysphagia is Associated With the Combination of Defective Bolus Transit and Poorly Relaxing Lower Esophageal Sphincter in Patients With Ineffective Esophageal Motility.

Dysphagia is a variable symptom associated with complex esophageal motility abnormalities. IEM patients with a combination of poorly relaxing LES and DBT are more likely to have dysphagia.

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Patients' Knowledge, Attitudes, and Practices Regarding Non-pharmacological Treatments for Irritable Bowel Syndrome.

IBS patients exhibit a significant gap between their positive attitudes and their actual practices concerning non-pharmacological treatments. Knowledge is a direct driver of practice, but positive attitudes alone are insufficient to translate into behavior. Healthcare providers must move beyond simply fostering positive attitudes and focus on targeted educational interventions that provide actionable knowledge and skills to improve patient outcomes.

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Real‑world Application of the International Anorectal Physiology Working Group Standardized Protocol and London Classification: A Multi‑country Cross‑sectional Survey of Anorectal Manometry Practice in Asia.

Across Asian centers, ARM practice shows marked regional variation and incomplete implementation of the IAPWG standardized protocol and London classification, highlighting persistent gaps in standardization. Strengthening procedural guidance, regionally appropriate normative data, and interpretation criteria through coordinated education and international collaboration is needed to support more consistent and clinically meaningful use of ARM in routine practice.

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Semaglutide Induces Changes in Gastric Electrical Activity in Patients With Overweight and Obesity: A Pilot Study.

Semaglutide appears to alter gastric electrical activity on BSGM and increase early satiation, offering potential biomarkers for detecting drug effects. Further studies are needed.

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Therapeutic Impact on Quality of Life in Adult Patients With Chronic Intestinal Pseudo-obstruction: A Multicenter, Cohort Study.

Patients with CIPO have a lower physical, psychological and social QOL, which is equivalent to or lower than that of adult patients with inflammatory bowel disease or psychiatric disorders. Sterilization of the intestinal tract and PEG-J decompression effectively improve the QOL of patients.

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link

Aliment Pharmacol Ther
Editorial: Beyond Resection-Rethinking Postoperative Management in Colonic Crohn's Disease.

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Review Article: Ileal Bile Acid Transport (IBAT) Inhibitors as an Emerging Treatment for Cholestatic Liver Disease.

IBAT inhibitors represent the first upstream pharmacotherapy targeting enterohepatic bile acid recirculation and are effective at reducing pruritus in ALGS and PFIC. Their role in PBC and PSC is promising yet undefined. Long-term studies are needed to assess effects on fibrosis progression, hepatocellular carcinoma risk and transplant-free survival.

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Clin Gastroenterol Hepatol
IBS Clinical Care Gaps and the Potential of Future Therapeutics based on Peripheral Visceral Afferent Modulation.

Evidence from predominantly pre-clinical and human studies supporting these peripheral targets is summarized, and provides the rationale to develop novel, peripherally-restricted pharmaceuticals to reduce visceral pain in IBS. Novel neuromodulators restricted to peripheral actions and targeting DRG receptors would constitute a novel alternative to central neuromodulators for IBS-pain, in addition to potential effects on colonic transit or secretion.

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MetALD in Women: Epidemiology, Natural History, and Clinical Outcomes.

This review synthesizes current evidence on the epidemiology, natural history, pathogenesis, and clinical outcomes of MetALD in women, highlight emerging data on the influence of reproductive health, psychiatric comorbidities, and socioeconomic factors in shaping disease trajectories. We conclude by identifying critical research gaps and propose future directions for developing person-centered, sex-specific approaches to the diagnosis and treatment of MetALD.

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Endosc Int Open
Flexible spectral imaging color enhancement in colon capsule endoscopy: Scoping review of evidence for lesion detection and characterization.

FICE may play a complementary role in CCE, significantly improving detection of high-risk flat/serrated lesions and providing objective data for differentiating adenomas from hyperplastic polyps. Integrating FICE into diagnostic workflows could provide a smart solution to address CCE high FER and cost-effectiveness barriers.

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Post-inflammatory polyps and risk of dysplasia in inflammatory bowel disease: Wolves in sheep's clothing?

Moreover, emerging evidence suggests that a minority of post-inflammatory-like lesions may conceal or coexist with dysplasia, underscoring the diagnostic challenge posed by polypoid lesions in chronically inflamed mucosa. In this article, we review the available data about the association between post-inflammatory polyps and development of CRC in IBD and discuss how advances in technology, particularly development of artificial intelligence models integrated with endoscopy, may contribute to their appropriate management.

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Gastrointest Endosc
A note from the Editor-in-Chief.

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Avoiding "Roux-do" surgery: lumen-apposing metal stents for partial endoscopic reversal of gastric bypass.

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Bypassing obstacles.

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Diagnosis of pancreatic cancers: beyond image enhancement.

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Endoscopic resection for cervical esophageal squamous cell carcinoma: small space, big impact.

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Endoscopic ultrasound-directed transenteric endoscopic retrograde cholangiopancreatography in surgically altered anatomy: one more step taken, many more to go.

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Innovation begins with what we already have.

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Optimizing traction-assisted endoscopic submucosal dissection: Is this novel robotic arm the much needed "helping hand"?

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Repeat examination in patients with previous incomplete colonoscopy has a high success rate and yield of colorectal neoplasia.

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Resect and repeat: Is this as good as it gets?

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Submucosal tunneling endoscopic resection for subepithelial tumors: dissecting the outcome.

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The role of artificial intelligence in colonoscopy performance and quality among gastroenterology fellows.

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The state, health, and future of Gastrointestinal Endoscopy.

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Toward the smart endoscopy center: evaluating the role of robots in the endoscopy unit.

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Withdrawal time in colonoscopy: one size does not fit all.

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J Neurogastroenterol Motil
Bridging the Therapeutic Gap: Clinical Efficacy of Endoscopic Radiofrequency Stretta Therapy for Gastroesophageal Reflux Disease in Korea.

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From Belief to Behavior: Closing the Knowledge-Practice Gap in Irritable Bowel Syndrome Self-management.

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Hydrogen and Methane Breath Test: The Asian Neurogastroenterology and Motility Association Monograph.

The Asian Neurogastroenterology and Motility Association hence presents the first Asian monograph guiding application and interpretation of breath test. The monograph was formulated according to the framework of indications, preparatory process, performance, and interpretation of results, as well as future direction for research.

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Towards a Standard Protocol for Fecal Microbiota Transplantation in Irritable Bowel Syndrome.

Administering the donor's fecal transplant into the small intestine results in durable effects of FMT and long-term colonization of beneficial bacteria. A standard protocol for FMT with large and durable effects should include (1) careful donor selection, (2) handling the donor's fecal transplant in a way that preserves its microbiota contents, and (3) administering the transplant into the small intestine.

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Miscellaneous

misc publications eg case reports, tools of the trade, images of the month, etc…

Am J Gastroenterol
An Unusual Culprit: Emphysematous Gastritis Due to Mycobacterium Mucogenicum.

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Endoscopic reconstruction of common bile duct transection after right hepatectomy using an innovative cholangioscopy-assisted ERCP-EUS rendezvous technique.

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Making Cents of the Cost of Helicobacter pylori Management.

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Clin Gastroenterol Hepatol
Areas with high prevalence of liver disease have more adverts for alcohol and unhealthy food.

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Fecal Microbiota Transplantation Rapidly Reduces Systemic Inflammation and Resolves C. difficile Pseudomembranous Colitis.

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Refining HEPAmet for treatment eligibility in MASLD: External Validation and Guardrail to Exclude Cirrhosis, Limit Early Disease.

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Update of geospatial clusters of colorectal cancer in the US to prioritize screening interventions - What has changed?

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Endosc Int Open
Successful endoscopic sphincterotomy using a rotatable sphincterotome in a patient with situs inversus totalis.

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Endoscopy
"Suture-first" endoscopic transection of a postoperative rectal mucosal bridge: a safety strategy to prevent adverse events.

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Endobiliary radiofrequency ablation for refractory cholangitis caused by mucin-producing intraductal papillary neoplasm of the bile duct.

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Endoscopic membranectomy for a 2-day-old neonate with duodenal membranous atresia: the youngest case reported.

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Endoscopic reconstruction of complete post-radiation esophageal and neopharyngeal obliteration.

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Endoscopic submucosal dissection using the water pressure method for superficial esophageal cancer within a cervical pseudodiverticulum.

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Endoscopic vacuum therapy successfully treats postoperative esophageal rupture after laparoscopic-assisted total gastrectomy: a full therapeutic course report.

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Flexible endoluminal robotic traction facilitates stable submucosal exposure during endoscopic submucosal dissection.

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Management of periampullary variceal bleeding with a biliary stent and endoscopic ultrasound-guided cyanoacrylate injection.

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Removal of biliary casts following orthotopic liver transplantation using a 2.5-mm ultra-fine choledochoscope via the 10-French T-tube tract.

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Rescue retrieval of a migrated and fractured biliary plastic stent using a rotatable spiral basket in Roux-en-Y anatomy.

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Troubleshooting of plastic stent impaction in the working channel during endoscopic ultrasound-guided hepaticogastrostomy.

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Underwater indirect clipping for colonic diverticular bleeding.

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Gastroenterology
Intestinal smooth muscle macrophages: linking the ENS and CNS in Parkinson's disease.

Pubmed   Journal   ReadQx 

Gut
Fluorescent virus lights up on a new drug for chronic hepatitis E.

Pubmed   Journal   ReadQx 

Loss of sinusoidal endothelial identity: RAP1A at the crossroads of capillarisation and liver fibrosis.

Pubmed   Journal   ReadQx 

Percutaneous needle decompression for endoscopic iatrogenic pneumoperitoneum: assessment of safety and efficacy in real world practice.

Pubmed   Journal   ReadQx 

Proton pump inhibitors should be continued after endoscopic variceal ligation.

Pubmed   Journal   ReadQx 

Hepatology
Two decades of Hepatitis E in solid organ transplantation: From endemic insight to unresolved therapeutic questions.

Pubmed   Journal   ReadQx 

J Hepatol
AI-based ECG diagnostic algorithm to detect patients at risk for chronic liver disease: are we ready for the consequences?

Pubmed   Journal   ReadQx 

FXR agonism in PSC recalibrated: How PRIMIS shapes endpoints and expectations for the next generation of trials.

Pubmed   Journal   ReadQx 


Letters&Replies

Letters to the editors and authors’ replies

Aliment Pharmacol Ther
Editorial-Fistula Calprotectin as a Biomarker of Local Inflammation and Treatment Response in Perianal Fistulising Crohn's Disease. Authors' Reply.

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Editorial: New Insights Into the Aetiopathogenesis of Post-Infective Irritable Bowel Syndrome and Functional Dyspepsia: A Significant Step Forward but What Next? Authors' Reply.

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Letter: Attempted Validation of Villin-1 as a Gut Barrier Marker in Decompensated Cirrhosis-Potential Confounding by Tubular Injury and Aetiology. Authors' Reply.

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Letter: Dose and Donor Matter-Determining the Optimal Strategy for Faecal Microbiota Transplantation in Clostridioides difficile Infection. Authors' Reply.

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Letter: Double PBC-Related Autoantibody Positivity-How Essential Is It for Diagnosis? Authors' Reply.

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Letter: Incremental Value and Outcome Modelling in Frailty Assessment for Older Patients with Inflammatory Bowel Disease. Author's Reply.

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Letter: Optimising Hepatitis B Vaccination in Inflammatory Bowel Disease-Expanding Strategies Beyond Double-Dose Recombinant Vaccination. Authors' Reply.

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Letter: Steroid Tapering in Ulcerative Colitis-The Importance of Disease Severity and Maintenance Therapy. Authors' Reply.

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Clin Gastroenterol Hepatol
Timing of Endoscopic Necrosectomy in Infected Walled-Off Necrosis: One Strategy Does Not Fit All.

Pubmed   Journal   ReadQx 

hEDS and the Nosology of Disorders of Gut Brain Interaction.

Pubmed   Journal   ReadQx 

Endosc Int Open
Automated video recording built into routine clinical practice: What does it take?

Pubmed   Journal   ReadQx 

Comment on the study by Fukuya et al. (2025).

Pubmed   Journal   ReadQx 

Gastroenterology
Unraveling the Functional Heterogeneity of Calprotectin Quaternary Structures in Inflammatory Bowel Disease.

Pubmed   Journal   ReadQx 

Gastrointest Endosc
An alternative method for nasojejunal tube placement.

Pubmed   Journal   ReadQx 

Beyond resection with no residual microscopic disease: the critical role of histologic risk stratification in endoscopic management of suspected deep submucosal invasive colorectal cancer.

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Endoscopic therapy for small neuroendocrine tumors of the rectum.

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Enhancing the rigor and clinical applicability of optical enhancement combined with magnification endoscopy for gastric lesion detection.

Pubmed   Journal   ReadQx 

From withdrawal time to technique: Can computer-aided quality assurance help change a colonoscopy quality indicator?

Pubmed   Journal   ReadQx 

Refining cost-effectiveness modeling of colorectal cancer screening in average-risk Asian populations: implications of risk-based stratification and free screening policies.

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Shifting the timing and readjusting the purpose of surveillance colonoscopy after piecemeal endoscopic mucosal resection of large colonic polyps in the era of margin thermal ablation.

Pubmed   Journal   ReadQx 

J Hepatol
Refining Risk Stratification and Care Pathways in Pediatric MASLD.

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J Neurogastroenterol Motil
Resolution of Refractory Gastroparesis Symptoms Following Benzodiazepine Treatment for Catatonic Depression.

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Substrate-dependent Differences of Colonic Hydrogen Production in a Patient With Fructose Malabsorption.

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